Evidence map›Paper›PMID 30101399›Full record

ArticlePlanta2018

A deep convolutional neural network approach for predicting phenotypes from genotypes.

Wenlong Ma, Zhixu Qiu, Jie Song, Jiajia Li, Qian Cheng, Jingjing Zhai, Chuang Ma

Abstract read
PubMed Publisher
In one paragraph

Article in Planta, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 144 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
144citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

144 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Genome-Enabled Prediction Methods Based on Machine Learning.Methods in molecular biology (Clifton, N.J.) · 2022
    Pooled it
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  6. Multi-variant GWAS and genomic prediction dissect the genetic architecture underlying tomato fruit weight.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
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  11. Achieving High-Density and Stress-Resilient Maize Breeding Via Germplasm Innovation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  12. Harnessing artificial intelligence in plant breeding: innovations in digital phenotyping and breeding methodologies.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Review
  13. Article
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  20. Article

84 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wenlong MaState Key Laboratory of Crop Stress Biology for Arid Areas, Center of Bioinformatics, College of Life Sciences, Northwest A&F University, Yangling, 712100, Shaanxi, China.
Zhixu QiuState Key Laboratory of Crop Stress Biology for Arid Areas, Center of Bioinformatics, College of Life Sciences, Northwest A&F University, Yangling, 712100, Shaanxi, China.
Jie SongState Key Laboratory of Crop Stress Biology for Arid Areas, Center of Bioinformatics, College of Life Sciences, Northwest A&F University, Yangling, 712100, Shaanxi, China.
Jiajia LiState Key Laboratory of Crop Stress Biology for Arid Areas, Center of Bioinformatics, College of Life Sciences, Northwest A&F University, Yangling, 712100, Shaanxi, China.
Qian ChengState Key Laboratory of Crop Stress Biology for Arid Areas, Center of Bioinformatics, College of Life Sciences, Northwest A&F University, Yangling, 712100, Shaanxi, China.
Jingjing ZhaiState Key Laboratory of Crop Stress Biology for Arid Areas, Center of Bioinformatics, College of Life Sciences, Northwest A&F University, Yangling, 712100, Shaanxi, China.
Chuang MaState Key Laboratory of Crop Stress Biology for Arid Areas, Center of Bioinformatics, College of Life Sciences, Northwest A&F University, Yangling, 712100, Shaanxi, China. cma@nwafu.edu.cn.ORCID http://orcid.org/0000-0001-9612-7898

Funding

National Natural Science Foundation of China 31570371the Agricultural Science and Technology Innovation and Research Project of Shaanxi Province, China 2015NY011the Innovative Talents Promotion Project of Shaanxi Province of China 2017KJXX-67
6 · The paper itself

Abstract

MAIN

conclusionDeep learning is a promising technology to accurately select individuals with high phenotypic values based on genotypic data. Genomic selection (GS) is a promising breeding strategy by which the phenotypes of plant individuals are usually predicted based on genome-wide markers of genotypes. In this study, we present a deep learning method, named DeepGS, to predict phenotypes from genotypes. Using a deep convolutional neural network, DeepGS uses hidden variables that jointly represent features in genotypes when making predictions; it also employs convolution, sampling and dropout strategies to reduce the complexity of high-dimensional genotypic data. We used a large GS dataset to train DeepGS and compared its performance with other methods. The experimental results indicate that DeepGS can be used as a complement to the commonly used RR-BLUP in the prediction of phenotypes from genotypes. The complementarity between DeepGS and RR-BLUP can be utilized using an ensemble learning approach for more accurately selecting individuals with high phenotypic values, even for the absence of outlier individuals and subsets of genotypic markers. The source codes of DeepGS and the ensemble learning approach have been packaged into Docker images for facilitating their applications in different GS programs.

Indexed as

Neural Networks, ComputerGenetic Association StudiesGenome-Wide Association StudyMachine LearningModels, GeneticPlantsSelection, GeneticDeep learningEnsemble learningGenomic selectionGenotypic markerHigh phenotypic valuesMachine learning

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.