Evidence map›Paper›PMID 30101369›Full record

ArticleRheumatology international2019

Evaluation of disease activity in a low-income juvenile idiopathic arthritis cohort.

Francisco Airton Castro Rocha, Joaquim Ivo Vasques Dantas Landim, Marcela Gondim Aguiar, João Pedro Emrich Accioly, Carolina Noronha Lechiu, Luiza Helena Acácio Costa, Carlos Nobre Rabelo Júnior, Leila Nascimento da Rocha, Hermano Alexandre Lima Rocha

Abstract read
PubMed Publisher
In one paragraph

Article in Rheumatology international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Microbes, helminths, and rheumatic diseases.Best practice & research. Clinical rheumatology · 2020
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Francisco Airton Castro RochaDepartment of Internal Medicine, Liga de Reumatologia e Doenças Autoimunes, Faculdade de Medicina, Federal University of Ceará, Fortaleza, Brazil. arocha@ufc.br.ORCID 0000-0003-4370-3294
Joaquim Ivo Vasques Dantas LandimDepartment of Internal Medicine, Liga de Reumatologia e Doenças Autoimunes, Faculdade de Medicina, Federal University of Ceará, Fortaleza, Brazil.ORCID 0000-0003-3237-2573
Marcela Gondim AguiarDepartment of Internal Medicine, Liga de Reumatologia e Doenças Autoimunes, Faculdade de Medicina, Federal University of Ceará, Fortaleza, Brazil.ORCID 0000-0002-3811-6020
João Pedro Emrich AcciolyDepartment of Internal Medicine, Liga de Reumatologia e Doenças Autoimunes, Faculdade de Medicina, Federal University of Ceará, Fortaleza, Brazil.ORCID 0000-0002-7147-7848
Carolina Noronha LechiuDepartment of Internal Medicine, Liga de Reumatologia e Doenças Autoimunes, Faculdade de Medicina, Federal University of Ceará, Fortaleza, Brazil.ORCID 0000-0003-3815-8236
Luiza Helena Acácio CostaDepartment of Internal Medicine, Liga de Reumatologia e Doenças Autoimunes, Faculdade de Medicina, Federal University of Ceará, Fortaleza, Brazil.ORCID 0000-0003-1538-0934
Carlos Nobre Rabelo JúniorRheumatology Service, Pediatric Rheumatology Division, Hospital Geral de Fortaleza, Fortaleza, CE, Brazil.ORCID 0000-0003-0614-8375
Leila Nascimento da RochaDepartment of Internal Medicine, Liga de Reumatologia e Doenças Autoimunes, Faculdade de Medicina, Federal University of Ceará, Fortaleza, Brazil.ORCID 0000-0002-2303-9392
Hermano Alexandre Lima RochaDepartment of Public Health, Federal University of Ceará, Fortaleza, Brazil.ORCID 0000-0001-9096-0969
Universidade Federal do Ceará · BRHospital Geral de Fortaleza · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 459334/2014-0
6 · The paper itself

Abstract

Determine disease activity in a low income juvenile idiopathic arthritis (JIA) cohort. 164 JIA patients from families with less than US$ 4500.00/capita mean annual income followed in Fortaleza-CE, Brazil, were cross-sectionally evaluated between May 2015-April 2016. Mean age was 14 ± 5.1 years (95 female) with 10.31 ± 3.7 years disease duration. Polyarticular category predominated, with 63 (38.4%) patients, followed by 40 (24%) enthesitis-related (ERA), and 36 (22%) oligoarticular. All but 1 out of 84 parents declared less than US$ 10,000.00 annual family income. Eighty-eight (60.7%) were receiving methotrexate and 19 (13%) leflunomide including 12 (63%) using both; 46 (28%) were on biologic DMARD including 20 (43.5%) adalimumab, 17 (41.5) etanercept, 5 (10.8%) tocilizumab, 2 (4.2%) abatacept, and 1 (2.1%) each on infliximab and canakinumab. Mean CHAQ and JADAS27 were 0.36 ± 0.55 and 5.31 ± 8.5, respectively. Thirty-two (20%) out of 159 patients had deformities. A bivariate analysis revealed that polyarticular had more deformities than oligoarticular patients (p = 0.002; OR = 2.389; 95% CI 1.37-4.14). Logistic regression showed no association between high JADAS and family income (p = 0.339; OR = 1.45; 95% CI 0.67-3.31). A general linear model showed significantly lower CHAQ score in patients from families earning more as compared to those earning less than 300.00 US$ monthly (p = 0.002). This study reports JIA disease activity in a low income population. Low income apparently did not influence prognosis given the low mean JADAS27 and CHAQ scores vis-à-vis data from other cohorts.

Indexed as

AbataceptAdalimumabAdolescentAntirheumatic AgentsArthritis, JuvenileBrazilChildCohort StudiesEtanerceptFemaleHumansMaleMethotrexatePovertyPrognosisSeverity of Illness IndexAbataceptAdalimumabAntirheumatic AgentsEtanerceptMethotrexateEpidemiologyJuvenile idiopathic arthritisPediatric rheumatology

Identifiers

PMID30101369
OpenAlexW2886482614

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.