Evidence map›Paper›PMID 30101336›Full record

ArticleBioinformatics (Oxford, England)2019

LipidFinder on LIPID MAPS: peak filtering, MS searching and statistical analysis for lipidomics.

Eoin Fahy, Jorge Alvarez-Jarreta, Christopher J Brasher, An Nguyen, Jade I Hawksworth, Patricia Rodrigues, Sven Meckelmann, Stuart M Allen, Valerie B O'Donnell

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Lipidome Complexity in Physiological and Pathological Skin Pigmentation.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Interpreting the lipidome: bioinformatic approaches to embrace the complexity.Metabolomics : Official journal of the Metabolomic Society · 2021
    Review
  16. Ecotoxico-lipidomics: An emerging concept to understand chemical-metabolic relationships in comparative fish models.Comparative biochemistry and physiology. Part D, Genomics & proteomics · 2020
    Review
  17. Review
  18. Article
  19. Lipidomics from sample preparation to data analysis: a primer.Analytical and bioanalytical chemistry · 2020
    Review
  20. Tutorial on lipidomics.Analytica chimica acta · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Eoin FahyDepartment of Bioengineering, University of California San Diego, San Diego, CA, USA.
Jorge Alvarez-JarretaInstitute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Christopher J BrasherInstitute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
An NguyenBabraham Institute, Babraham Research Campus, Cambridge, UK.
Jade I HawksworthInstitute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Patricia RodriguesInstitute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Sven MeckelmannInstitute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Stuart M AllenSchool of Computer Science and Informatics, Cardiff University, Cardiff, UK.
Valerie B O'DonnellInstitute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.

Funding

Wellcome Trust 203014/Z/16/Z
6 · The paper itself

Abstract

summaryWe present LipidFinder online, hosted on the LIPID MAPS website, as a liquid chromatography/mass spectrometry (LC/MS) workflow comprising peak filtering, MS searching and statistical analysis components, highly customized for interrogating lipidomic data. The online interface of LipidFinder includes several innovations such as comprehensive parameter tuning, a MS search engine employing in-house customized, curated and computationally generated databases and multiple reporting/display options. A set of integrated statistical analysis tools which enable users to identify those features which are significantly-altered under the selected experimental conditions, thereby greatly reducing the complexity of the peaklist prior to MS searching is included. LipidFinder is presented as a highly flexible, extensible user-friendly online workflow which leverages the lipidomics knowledge base and resources of the LIPID MAPS website, long recognized as a leading global lipidomics portal. AVAILABILITY AND IMPLEMENTATION: LipidFinder on LIPID MAPS is available at: http://www.lipidmaps.org/data/LF.

Indexed as

Databases, FactualSoftwareChromatography, LiquidComputational BiologyKnowledge BasesLipidsMass SpectrometryWorkflowLipids

Identifiers

PMID30101336
PMCPMC6378932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.