ArticleGigaScience2018
Draft genome assembly of the invasive cane toad, Rhinella marina.
Article in GigaScience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 78 citations in OpenAlex.
- Annotated genome of the Atlantic dog whelk, Nucella lapillus.G3 (Bethesda, Md.) · 2025Article
- Genome assembly of the endangered Santa Marta Harlequin Toad, Atelopus laetissimus, endemic to the Sierra Nevada de Santa Marta of Colombia.The Journal of heredity · 2025Article
- Repeat-Rich Regions Cause False-Positive Detection of NUMTs: A Case Study in Amphibians Using an Improved Cane Toad Reference Genome.Genome biology and evolution · 2024Article
- Comprehensive Analysis of Bufadienolide and Protein Profiles of Gland Secretions from MedicinalToxins · 2024Article
- Is developmental plasticity triggered by DNA methylation changes in the invasive cane toad (Ecology and evolution · 2024Article
- Whole-mitogenome analysis unveils previously undescribed genetic diversity in cane toads across their invasion trajectory.Ecology and evolution · 2024Article
- The paddy frog genome provides insight into the molecular adaptations and regulation of hibernation in ectotherms.iScience · 2024Article
- Article
- Comparative genomics reveals insights into anuran genome size evolution.BMC genomics · 2023Article
- Chromosome-level genome assembly of a high-altitude-adapted frog (Rana kukunoris) from the Tibetan plateau provides insight into amphibian genome evolution and adaptation.Frontiers in zoology · 2023Article
- Article
- Draft genome and multi-tissue transcriptome assemblies of the Neotropical leaf-frog Phyllomedusa bahiana.G3 (Bethesda, Md.) · 2022Article
- Cryptic lineages and standing genetic variation across independent cane toad introductions.Molecular ecology · 2022Article
- Transcript- and annotation-guided genome assembly of the European starling.Molecular ecology resources · 2022Article
- Vasoconstrictor and hemodynamic effects of a methanolic extract from Rhinella marina toad poison.Toxicon : official journal of the International Society on Toxinology · 2022Article
- Evolutionary dynamics of DIRS-like and Ngaro-like retrotransposons in Xenopus laevis and Xenopus tropicalis genomes.G3 (Bethesda, Md.) · 2022Article
- Evolutionary analyses of visual opsin genes in frogs and toads: Diversity, duplication, and positive selection.Ecology and evolution · 2022Article
- A dense linkage map for a large repetitive genome: discovery of the sex-determining region in hybridizing fire-bellied toads (Bombina bombina and Bombina variegata).G3 (Bethesda, Md.) · 2021Article
- Transposable elements expression in Rhinella marina (cane toad) specimens submitted to immune and stress challenge.Genetica · 2021Article
- Pseudogenized Amelogenin Reveals Early Tooth Loss in True Toads (Anura: Bufonidae).Integrative and comparative biology · 2021Article
Corrections and comments
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Authors and funding
15 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The cane toad (Rhinella marina formerly Bufo marinus) is a species native to Central and South America that has spread across many regions of the globe. Cane toads are known for their rapid adaptation and deleterious impacts on native fauna in invaded regions. However, despite an iconic status, there are major gaps in our understanding of cane toad genetics. The availability of a genome would help to close these gaps and accelerate cane toad research. Findings: We report a draft genome assembly for R. marina, the first of its kind for the Bufonidae family. We used a combination of long-read Pacific Biosciences RS II and short-read Illumina HiSeq X sequencing to generate 359.5 Gb of raw sequence data. The final hybrid assembly of 31,392 scaffolds was 2.55 Gb in length with a scaffold N50 of 168 kb. BUSCO analysis revealed that the assembly included full length or partial fragments of 90.6% of tetrapod universal single-copy orthologs (n = 3950), illustrating that the gene-containing regions have been well assembled. Annotation predicted 25,846 protein coding genes with similarity to known proteins in Swiss-Prot. Repeat sequences were estimated to account for 63.9% of the assembly. Conclusions: The R. marina draft genome assembly will be an invaluable resource that can be used to further probe the biology of this invasive species. Future analysis of the genome will provide insights into cane toad evolution and enrich our understanding of their interplay with the ecosystem at large.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.