Evidence map›Paper›PMID 30101279›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2019

Consensus on Shared Measures of Mobility and Cognition: From the Canadian Consortium on Neurodegeneration in Aging (CCNA).

Manuel Montero-Odasso, Quincy J Almeida, Louis Bherer, Amer M Burhan, Richard Camicioli, Julien Doyon, Sarah Fraser, Susan Muir-Hunter, Karen Z H Li, Teresa Liu-Ambrose and 12 more

Open access · hybridAbstract readConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed, 3 pooled it
13.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 3 syntheses or guidelines pooled it, 178 citations in OpenAlex.

  1. Pooled it
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  3. Recommendations of the 5th Canadian Consensus Conference on the diagnosis and treatment of dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2020
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30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 15 institutions in 3 countries.

Manuel Montero-OdassoDepartment of Medicine, Division of Geriatric Medicine, University of Western Ontario, London, Canada.
Quincy J AlmeidaDepartment of Kinesiology and Physical Education, Sun Life Financial Movement Disorders Research Centre, Wilfrid Laurier University, Waterloo, Ontario, Canada.
Louis BhererDepartment of Psychology and PERFORM Centre, Concordia University, Montréal, Quebec, Canada.
Amer M BurhanDepartment of Psychiatry, Geriatric Psychiatry, Schulich School of Medicine, University of Western Ontario, London, Canada.
Richard CamicioliDepartment of Medicine, Geriatric and Cognitive Neurology, University of Alberta, Edmonton, Canada.
Julien DoyonFunctional Neuroimaging Unit, University of Montreal, Quebec, Canada.
Sarah FraserInterdisciplinary School of Health Sciences, Faculty of Health Sciences, University of Ottawa, Ontario, Canada.
Susan Muir-HunterDepartment of Medicine, Division of Geriatric Medicine, University of Western Ontario, London, Canada.
Karen Z H LiDepartment of Psychology and PERFORM Centre, Concordia University, Montréal, Quebec, Canada.
Teresa Liu-AmbroseDepartment of Physical Therapy, Centre for Hip Health and Mobility, University of British Columbia, Canada.
William McIlroyDivision of Neurology and Department of Medicine, University of Toronto, Ontario, Canada.
Laura MiddletonDepartment of Kinesiology, University of Waterloo, Ontario, Canada.
José A MoraisDepartment of Medicine, Division of Geriatrics and Centre of Excellence in Aging and Chronic Disease, McGill University, Montréal, Quebec, Canada.
Ryota SakuraiGait and Brain Lab, Parkwood Institute, Lawson Health Research Institute, London, Ontario, Canada.
Mark SpeechleyDepartment of Epidemiology and Biostatistics, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Canada.
Akshya VasudevDepartment of Psychiatry, Geriatric Psychiatry, Schulich School of Medicine, University of Western Ontario, London, Canada.
Olivier BeauchetDepartment of Medicine, Division of Geriatric Medicine, McGill University, Montréal, Quebec, Canada.
Jeffrey M HausdorffCenter for the Study of Movement, Cognition and Mobility, Neurological Institute, Tel Aviv Sourasky Medical Center, Israel.
Caterina RosanoDepartment of Epidemiology, University of Pittsburgh, Pennsylvania.
Stephanie StudenskiDivision of Geriatric Medicine, School of Medicine, University of Pittsburgh, Pennsylvania.
Joe VergheseDepartment of Medicine, Albert Einstein College of Medicine, Bronx, New York.
Canadian Gait and Cognition Network
Western University · CAUniversité de Montréal · CAUniversity of Pittsburgh · USAlbert Einstein College of Medicine · USConcordia University · CAJewish General Hospital · CALawson Health Research Institute · CAMcGill University · CATel Aviv University · ILUniversity of Alberta · CAUniversity of Ottawa · CAUniversity of Toronto · CAUniversity of Waterloo · CAVancouver Coastal Health · CAWilfrid Laurier University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA new paradigm is emerging in which mobility and cognitive impairments, previously studied, diagnosed, and managed separately in older adults, are in fact regulated by shared brain resources. Deterioration in these shared brain mechanisms by normal aging and neurodegeneration increases the risk of developing dementia, falls, and fractures. This new paradigm requires an integrated approach to measuring both domains. We aim to identify a complementary battery of existing tests of mobility and cognition in community-dwelling older adults that enable assessment of motor-cognitive interactions.

methodsExperts on mobility and cognition in aging participated in a semistructured consensus based on the Delphi process. After performing a scoping review to select candidate tests, multiple rounds of consultations provided structured feedback on tests that captured shared characteristics of mobility and cognition. These tests needed to be sensitive to changes in both mobility and cognition, applicable across research studies and clinics, sensitive to interventions, feasible to perform in older adults, been previously validated, and have minimal ceiling/floor effects.

resultsFrom 17 tests appraised, 10 tests fulfilled prespecified criteria and were selected as part of the "Core-battery" of tests. The expert panel also recommended a "Minimum-battery" of tests that included gait speed, dual-task gait speed, the Montreal Cognitive Assessment and Trail Making Test A&B.

conclusionsA standardized assessment battery that captures shared characteristics of mobility and cognition seen in aging and neurodegeneration may increase comparability across research studies, detection of subtle or common reversible factors, and accelerate research progress in dementia, falls, and aging-related disabilities.

Indexed as

Mobility LimitationAgedCanadaCognition DisordersDelphi TechniqueFemaleGeriatric AssessmentHumansMaleNeurodegenerative DiseasesAgingCognitionConsensusFallsGaitMobilityNeurodegenerative diseases

Identifiers

PMID30101279
PMCPMC6521916
OpenAlexW2809067122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.