ArticleFrontiers in oncology2018
Quantitative Analysis of
Article in Frontiers in oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 27 citations in OpenAlex.
- Variant-specific RNA testing resolves variants of uncertain significance in exome testing.BMC genomics · 2026Article
- Reclassification ofBiomolecules & biomedicine · 2026Article
- Utility of Targeted RNA Analysis in Neurogenetic Disorders.Neurology. Genetics · 2026Article
- A Plot Twist: When RNA Yields Unexpected Findings in Paired DNA-RNA Germline Genetic Testing.Genes · 2025Article
- Clinical, splicing, and functional analysis to classify BRCA2 exon 3 variants: Application of a points-based ACMG/AMP approach.Human mutation · 2022Article
- Mutational and splicing landscape in a cohort of 43,000 patients tested for hereditary cancer.NPJ genomic medicine · 2022Article
- Article
- RNA sequencing uncovers clinically actionable germline intronicBMJ case reports · 2022Article
- Classification of the canonical splice alterationCold Spring Harbor molecular case studies · 2022Article
- Article
- Reticular dysgenesis caused by an intronic pathogenic variant inCold Spring Harbor molecular case studies · 2020Article
- Cancer Genetic Counseling-Current Practice and Future Challenges.Cold Spring Harbor perspectives in medicine · 2020Review
- High-throughput functional evaluation of BRCA2 variants of unknown significance.Nature communications · 2020Article
- Contribution of mRNA Splicing to Mismatch Repair Gene Sequence Variant Interpretation.Frontiers in genetics · 2020Article
- Splicing profile by capture RNA-seq identifies pathogenic germline variants in tumor suppressor genes.NPJ precision oncology · 2020Article
- Assessment of Diagnostic Outcomes of RNA Genetic Testing for Hereditary Cancer.JAMA network open · 2019Article
- Impact of RNA testing on cardiac variant interpretation and patient management.HeartRhythm case reports · 2019Article
- Minigene Splicing Assays Identify 12 Spliceogenic Variants ofFrontiers in genetics · 2019Article
- Specifications of the ACMG/AMP variant curation guidelines for the analysis of germline CDH1 sequence variants.Human mutation · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Clinical genetic testing for hereditary breast and ovarian cancer (HBOC) is becoming widespread. However, the interpretation of variants of unknown significance (VUS) in HBOC genes, such as the clinically actionable genes
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.