Evidence map›Paper›PMID 30100997›Full record

ArticleOncotarget2018

Viral DNA integration and methylation of human papillomavirus type 16 in high-grade oral epithelial dysplasia and head and neck squamous cell carcinoma.

Sujita Khanal, Brian S Shumway, Maryam Zahin, Rebecca A Redman, John D Strickley, Patrick J Trainor, Shesh N Rai, Shin-Je Ghim, Alfred Bennett Jenson, Joongho Joh

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Sujita KhanalDivision of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Brian S ShumwayDepartment of Surgical and Hospital Dentistry, University of Louisville School of Dentistry, Louisville, KY, USA.
Maryam ZahinJames Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA.
Rebecca A RedmanJames Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA.
John D StrickleyJames Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA.
Patrick J TrainorJames Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA.
Shesh N RaiJames Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA.
Shin-Je GhimJames Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA.
Alfred Bennett JensonJames Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA.
Joongho JohJames Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA.
James Graham Brown Foundation · USUniversity of Louisville · USFred Hutch Cancer Center · USUniversity of Louisville Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the integration and methlyation of human papillomavirus type 16 (HPV16) in head and neck squamous cell carcinoma (HNSCC) and its oral precursor, high-grade oral epithelial dysplasia (hgOED). Archival samples of HPV16-positive hgOED (

Indexed as

head and neck cancerhigh-grade oral epithelial dysplasia (hgOED)HPV integrationHPV methylationhuman papillomavirus (HPV)

Identifiers

PMID30100997
PMCPMC6084396
OpenAlexW2883647223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.