Evidence map›Paper›PMID 30100944›Full record

ArticleNuclear medicine and molecular imaging2018

Prevalence and Risk Factors of Atypical Femoral Fracture Bone Scintigraphic Feature in Patients Experiencing Bisphosphonate-Related Osteonecrosis of the Jaw.

Chang-Hee Lee, Seung Hyun Son, Chae Moon Hong, Ju Hye Jeong, Shin Young Jeong, Sang-Woo Lee, Jaetae Lee, Tae-Geon Kwon, Byeong-Cheol Ahn

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Non-Viral Delivery System and Targeted Bone Disease Therapy.International journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Chang-Hee Lee1Department of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Seung Hyun Son1Department of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Chae Moon Hong1Department of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Ju Hye Jeong1Department of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Shin Young Jeong1Department of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Sang-Woo Lee1Department of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Jaetae Lee1Department of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Tae-Geon Kwon3Department of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University, Daegu, South Korea.
Byeong-Cheol Ahn1Department of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.ORCID 0000-0001-7700-3929
Kyungpook National University Hospital · KRKyungpook National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBisphosphonate (BP) is the first-line therapy for the management of osteoporosis. BP-related osteonecrosis of the jaw (BRONJ) and atypical femoral fracture (AFF) are increasingly common comorbidities in patients with osteoporosis under long-term BP treatment. The aim of this study was to evaluate the incidence and risk factors for AFF features on bone scintigraphy in patients with BRONJ.

methodsAmong total of 373 BRONJ patients treated between September 2005 and July 2014, 237 (220 women, 17 men; median age 73 years) who underwent three-phase bone scintigraphy were enrolled for this retrospective study. AFF features on bone scintigraphy and the related clinical factors were assessed.

resultsAmong 237 patients with BRONJ, 11 (4.6%) showed AFF features on bone scintigraphy. BP medication duration (

conclusionThe incidence of AFF features on bone scintigraphy was relatively high in patients with BRONJ. A careful observation of patients presenting with the AFF features on bone scintigraphy may be needed, particularly for female BRONJ patients with osteoporosis who have been on BP medication for over 34 months.

Indexed as

Atypical femoral fractureBisphosphonate-related osteonecrosis of the jawBone scintigraphyPrevalence

Identifiers

PMID30100944
PMCPMC6066490
OpenAlexW2883939539

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.