ArticleFrontiers in genetics2018
Genetic Susceptibility to Neurodegeneration in Amazon: Apolipoprotein E Genotyping in Vulnerable Populations Exposed to Mercury.
Article in Frontiers in genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 56 citations in OpenAlex.
- Article
- Genetic Modulation of Mercury Exposure on Perinatal and Birth Outcomes: A Systematic Review and Meta-Analysis of Gene-Environment Interactions.Journal of xenobiotics · 2026Review
- Genetic susceptibility to mercury in the amazon: A cross-sectional approach to snps analyses in exposed riverine populations.Genetics and molecular biology · 2026Article
- Binding of Hg(I) and Hg(II) Ions to Amyloid-Beta (Aβ) Peptide Variants Affect their Structure and Aggregation.Chembiochem : a European journal of chemical biology · 2025Article
- A Brazilian Minamata disease? Neurologists must be aware of mercury exposure and intoxication.Arquivos de neuro-psiquiatria · 2025Review
- Mercury Exposure and Health Effects in Indigenous People from the Brazilian Amazon-Literature-Scoping Review.International journal of environmental research and public health · 2025Article
- Concentrations of the serum long-chain omega-3 polyunsaturated fatty acids and hair mercury in men in different apolipoprotein E phenotypes.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
- Raising awareness of riverine populations in the Brazilian Amazon about MeHg intoxication inFrontiers in toxicology · 2025Article
- Mercury Contamination and Co-exposures in the Amazon Basin: At the Center of the Planetary Environmental Crisis.Annals of global health · 2025Review
- Environmental pollution challenges public health surveillance: the case of mercury exposure and intoxication in Brazil.Lancet regional health. Americas · 2024Review
- Trends in Mercury Contamination Distribution among Human and Animal Populations in the Amazon Region.Toxics · 2024Review
- Revisiting Genetic Influence on Mercury Exposure and Intoxication in Humans: A Scoping Review.Toxics · 2023Article
- Global Human Threat: The Potential Synergism between Mercury Intoxication and COVID-19.International journal of environmental research and public health · 2023Article
- Maternal methylmercury exposure during early-life periods adversely affects mature enamel structure of offspring rats at human exposure levels: a concern for oral health.Frontiers in public health · 2023Article
- Article
- Mercury Ion Binding to Apolipoprotein E Variants ApoE2, ApoE3, and ApoE4: Similar Binding Affinities but Different Structure Induction Effects.ACS omega · 2022Article
- Methylmercury exposure during prenatal and postnatal neurodevelopment promotes oxidative stress associated with motor and cognitive damages in rats: an environmental-experimental toxicology study.Toxicology reports · 2022Article
- Contributing to Understand the Crosstalk between Brain and Periphery in Methylmercury Intoxication: Neurotoxicity and Extracellular Vesicles.International journal of molecular sciences · 2021Article
- Neurological Impacts of Chronic Methylmercury Exposure in Munduruku Indigenous Adults: Somatosensory, Motor, and Cognitive Abnormalities.International journal of environmental research and public health · 2021Article
- An Assessment of Health Outcomes and Methylmercury Exposure in Munduruku Indigenous Women of Childbearing Age and Their Children under 2 Years Old.International journal of environmental research and public health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human exposure to mercury is a serious problem of public health in Amazon. As in other vulnerable populations throughout the world, Amazonian riverine populations are chronically exposed to this metal and some symptoms of mercury intoxication were already detected in these populations. However, studies on the genetic susceptibility to mercury toxicity in the Amazon are scarce, and they tested a limited number of individuals. In this context, apolipoprotein E gene (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.