Evidence map›Paper›PMID 30100814›Full record

ArticleJournal of inclusion phenomena and macrocyclic chemistry2018

Effects of inclusion of cetirizine hydrochloride in β-cyclodextrin.

Magdalena Paczkowska, Mikołaj Mizera, Kornelia Lewandowska, Maciej Kozak, Andrzej Miklaszewski, Judyta Cielecka-Piontek

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of inclusion phenomena and macrocyclic chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Magdalena Paczkowska1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Poznan University of Medical Sciences, Grunwaldzka 6, 60-780 Poznan, Poland.
Mikołaj Mizera1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Poznan University of Medical Sciences, Grunwaldzka 6, 60-780 Poznan, Poland.
Kornelia Lewandowska2Department of Molecular Crystals, Institute of Molecular Physics, Polish Academy of Sciences, Smoluchowskiego 17, 60-179 Poznan, Poland.
Maciej Kozak3Department of Macromolecular Physics, Adam Mickiewicz University, Umultowska 85, 61-614 Poznan, Poland.
Andrzej Miklaszewski4Institute of Materials Science and Engineering, Poznan University of Technology, Jana Pawła II 24, 60-965 Poznan, Poland.
Judyta Cielecka-Piontek1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Poznan University of Medical Sciences, Grunwaldzka 6, 60-780 Poznan, Poland.
Poznan University of Medical Sciences · PLAdam Mickiewicz University in Poznań · PLPolish Academy of Sciences · PLPoznań University of Technology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following the preparation of inclusion complex of cetirizine (CTZ) and β-cyclodextrin (β-CD), the compound was investigated to assess the possibility of modifying the physicochemical properties (solubility, release, stability, permeability) of CTZ after complexation that are vital for subsequent formulation studies involving the said complex. Changes in FT-IR/Raman spectra, DSC thermograms and XRD diffractograms confirmed the formation of a CTZ-β-CD system. Hydrophilic interaction chromatography with a DAD detector was employed to determine alterations of the CTZ concentration during studies following complexation. An analysis of a phase-solubility diagram of c

Indexed as

Cetirizine hydrochlorideChemical stabilityPermeabilityQuantum chemical calculationsSolubilityβ-Cyclodextrin

Identifiers

PMID30100814
PMCPMC6061035
OpenAlexW2801153342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.