Evidence map›Paper›PMID 30100713›Full record

ArticlePatient preference and adherence2018

The association of therapeutic versus recreational marijuana use and antiretroviral adherence among adults living with HIV in Florida.

Zachary L Mannes, Larry E Burrell, Erin G Ferguson, Zhi Zhou, Huiyin Lu, Charurut Somboonwit, Robert L Cook, Nicole Ennis

Open access · goldAbstract read
In one paragraph

Article in Patient preference and adherence, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Zachary L MannesDepartment of Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA, nennis@phhp.ufl.edu.
Larry E BurrellDepartment of Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA, nennis@phhp.ufl.edu.
Erin G FergusonDepartment of Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA, nennis@phhp.ufl.edu.
Zhi ZhouDepartment of Epidemiology, College of Public Health and Health Professions.
Huiyin LuDepartment of Biostatistics, College of Public Health and Health Professions.
Charurut SomboonwitDepartment of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
Robert L CookDepartment of Epidemiology, College of Public Health and Health Professions.
Nicole EnnisDepartment of Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA, nennis@phhp.ufl.edu.
University of Florida Health · USUniversity of Florida · USUniversity of South Florida · US

Funding

Southern HIV and Alcohol Research Consortium Administrative and Research Support CoreU24AA022002 · NIAAA · UNIVERSITY OF FLORIDA · PI COOK, ROBERT L · 2012 to 2022
$5.5M
UF Substance Abuse Training Center in Public HealthT32DA035167 · NIDA · UNIVERSITY OF FLORIDA · PI Linda B. Cottler · 2014 to 2026
$4.8M
Feasibility of SBIRT for Underserved HIV+ Adults 50+ in Primary Care SettingsK23DA039769 · NIDA · UNIVERSITY OF FLORIDA · PI ENNIS, NICOLE · 2016 to 2020
$769k
NIAAA NIH HHS U24 AA022002NIDA NIH HHS K23 DA039769NIDA NIH HHS T32 DA035167
6 · The paper itself

Abstract

purposeMarijuana use is common among people living with HIV (PLWH), but its association with antiretroviral therapy (ART) adherence is unclear. This study examined the association between reason for marijuana use and ART adherence in a sample of adults living with HIV. PATIENTS AND

methodsParticipants (N=703) recruited from seven community health centers in Florida completed a 45-minute questionnaire assessing demographics, symptoms of anxiety and depression, ART adherence, and substance use, including reasons for marijuana use. ART adherence was defined as the proportion of days in the last 30 days participants did not miss any medication and dichotomized as optimal (≥95%) and suboptimal (<95%). Multivariate logistic regression analysis assessed the association between therapeutic marijuana use to manage HIV symptoms (ie, improve appetite/gain weight, induce sleep, relieve nausea/vomiting, relieve pain, relieve anxiety/depression/stress) versus recreational marijuana use and ART adherence.

resultsApproximately one third (33.2%) of the participants reported using marijuana in the past 3 months. Of marijuana users, 21.8% reported using marijuana only for therapeutic purposes to manage HIV-associated medical symptoms, while 78.2% reported recreational use. After controlling for covariates, therapeutic use of marijuana was not associated with ART adherence (AOR =1.19, 95% CI =0.60-2.38,

conclusionOur results suggest differences in ART adherence between individuals who report recreational versus therapeutic marijuana use. Continued research examining the health implications of marijuana use among adults living with HIV is important as legalization of recreational and medical marijuana proliferates in the United States.

Indexed as

antiretroviral adherenceantiretroviral therapyHIV/AIDSmarijuana use

Identifiers

PMID30100713
PMCPMC6067624
OpenAlexW2884011402

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.