Evidence map›Paper›PMID 30100632›Full record

ArticleMonatshefte fur chemie2018

Synthesis of unsymmetrical disulfanes bearing 1,2,4-triazine scaffold and their in vitro screening towards anti-breast cancer activity.

Danuta Branowska, Justyna Ławecka, Mariusz Sobiczewski, Zbigniew Karczmarzyk, Waldemar Wysocki, Ewa Wolińska, Ewa Olender, Barbara Mirosław, Alicja Perzyna, Anna Bielawska and 1 more

Abstract read
In one paragraph

Article in Monatshefte fur chemie, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Micronutrient Status and Breast Cancer: A Narrative Review.International journal of molecular sciences · 2024
    Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. QSAR study of unsymmetrical aromatic disulfides as potent avian SARS-CoV main protease inhibitors using quantum chemical descriptors and statistical methods.Chemometrics and intelligent laboratory systems : an international journal sponsored by the Chemometrics Society · 2021
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Danuta BranowskaFaculty of Science, Siedlce University, 3 Maja 54, 08-110 Siedlce, Poland.
Justyna ŁaweckaFaculty of Science, Siedlce University, 3 Maja 54, 08-110 Siedlce, Poland.
Mariusz SobiczewskiFaculty of Science, Siedlce University, 3 Maja 54, 08-110 Siedlce, Poland.
Zbigniew KarczmarzykFaculty of Science, Siedlce University, 3 Maja 54, 08-110 Siedlce, Poland.
Waldemar WysockiFaculty of Science, Siedlce University, 3 Maja 54, 08-110 Siedlce, Poland.ORCID 0000-0002-3205-114X
Ewa WolińskaFaculty of Science, Siedlce University, 3 Maja 54, 08-110 Siedlce, Poland.
Ewa OlenderFaculty of Science, Siedlce University, 3 Maja 54, 08-110 Siedlce, Poland.
Barbara Mirosław2Department of Crystallography, Faculty of Chemistry, Maria Curie-Skłodowska University, Pl. Marii Curie-Sklodowskiej 3, 20-031 Lublin, Poland.
Alicja PerzynaFaculty of Science, Siedlce University, 3 Maja 54, 08-110 Siedlce, Poland.
Anna Bielawska3Department of Medicinal Chemistry and Drug Technology, Medical University of Bialystok, J. Kilinskiego 1, 15-089 Bialystok, Poland.
Krzysztof Bielawski3Department of Medicinal Chemistry and Drug Technology, Medical University of Bialystok, J. Kilinskiego 1, 15-089 Bialystok, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

abstractA new series of 1,2,4-triazine unsymmetrical disulfanes were prepared and evaluated as anticancer activity compounds against MCF-7 human breast cancer cells with some of them acting as low micromolar inhibitors. Evaluation of the cytotoxicity using an MTT assay, the inhibition of [ GRAPHICAL ABSTRACT:

Indexed as

Anticancer activityConformational analysisDisulfanesMolecular dockingX-ray structure determination

Identifiers

PMID30100632
PMCPMC6060961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.