Evidence map›Paper›PMID 30100082›Full record

ReviewPET clinics2018

Imaging Tumor Proliferation in Breast Cancer: Current Update on Predictive Imaging Biomarkers.

Azadeh Elmi, Elizabeth S McDonald, David Mankoff

Abstract readReview
In one paragraph

Review in PET clinics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Breast CancerJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020
    Article
  8. Article
  9. Cell-Proliferation Imaging for Monitoring Response to CDK4/6 Inhibition Combined with Endocrine-Therapy in Breast Cancer: Comparison of [Clinical cancer research : an official journal of the American Association for Cancer Research · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Azadeh ElmiDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA.
Elizabeth S McDonaldDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA.
David MankoffDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA. Electronic address: david.mankoff@uphs.upenn.edu.

Funding

RESEARCH TRACK RADIOLOGY RESIDENCYT32EB004311 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI Terence P Gade, Misun Hwang · 2005 to 2026
$4.5M
NIBIB NIH HHS T32 EB004311
6 · The paper itself

Abstract

Uncontrolled growth is a hallmark of cancer; imaging cell proliferation can provides an early indicator of therapeutic response. This capability is especially well-matched to the emerging cell cycle-specific chemotherapeutics with the goal of identifying patients that benefit from these treatments early in the course of treatment to guide personalized therapy. This article focuses on investigational cell proliferation imaging PET radiotracers to evaluate tumor proliferation in the setting of cell cycle-targeted chemotherapy and endocrine therapy for metastatic breast cancer.

Indexed as

RadiopharmaceuticalsBiomarkers, TumorBreast NeoplasmsCell ProliferationFemaleHumansPositron-Emission TomographyPredictive Value of TestsBiomarkers, TumorRadiopharmaceuticalsBreast cancerPET imagingRadiotracerTargeted therapiesTumor proliferation

Identifiers

PMID30100082
PMCPMC6092945

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.