Evidence map›Paper›PMID 30099827›Full record

ReviewCancer science2018

Fatty pancreas: A possible risk factor for pancreatic cancer in animals and humans.

Mami Takahashi, Mika Hori, Rikako Ishigamori, Michihiro Mutoh, Toshio Imai, Hitoshi Nakagama

Open access · goldAbstract readReview
In one paragraph

Review in Cancer science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 1 synthesis or guideline pooled it, 114 citations in OpenAlex.

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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mami TakahashiCentral Animal Division, National Cancer Center Research Institute, Tokyo, Japan.ORCID http://orcid.org/0000-0001-5062-811X
Mika HoriDepartment of Molecular Innovation in Lipidology, National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan.
Rikako IshigamoriCentral Animal Division, National Cancer Center Research Institute, Tokyo, Japan.
Michihiro MutohEpidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan.ORCID http://orcid.org/0000-0003-2054-7655
Toshio ImaiCentral Animal Division, National Cancer Center Research Institute, Tokyo, Japan.
Hitoshi NakagamaNational Cancer Center, Tokyo, Japan.
National Cerebral and Cardiovascular Center · JP

Funding

Grant-in-Aid for Scientific Research from the Japan Society for the Promotion of Science 15K14393Grant-in-Aid for Scientific Research from the Japan Society for the Promotion of Science 18K07081Grant-in-Aid for Scientific Research from the Japan Society for the Promotion of Science 25290049grant of the Third-Term Comprehensive 10-Year Strategy for Cancer Control from the Ministry of Health, Labor, and Welfare of JapanGrants-in-Aid for Cancer Research from the Ministry of Health, Labour, and Welfare of Japan and Management Expenses Grants from the Government to the National Cancer Center 21-2-1Grants-in-Aid from the Foundation for Promotion of Cancer Research and the Pancreas Research Foundation of JapanNational Cancer Center Research Core FacilityResearch Grant of the Princess Takamatsu Cancer Research Fund
6 · The paper itself

Abstract

Obesity, type 2 diabetes mellitus (T2DM) and aging are associated with pancreatic cancer risk, but the mechanisms of pancreatic cancer development caused by these factors are not clearly understood. Syrian golden hamsters are susceptible to N-nitrosobis(2-oxopropyl)amine (BOP)-induced pancreatic carcinogenesis. Aging, BOP treatment and/or a high-fat diet cause severe and scattered fatty infiltration (FI) of the pancreas with abnormal adipokine production and promote pancreatic ductal adenocarcinoma (PDAC) development. The KK-A

Indexed as

Adipose TissueAnimalsCarcinogensDiabetes Mellitus, Type 2Diet, High-FatDisease Models, AnimalHumansObesityPancreasPancreatic NeoplasmsRisk FactorsCarcinogenscancer susceptibilityfatty infiltrationobesitypancreatic cancertype 2 diabetes mellitus

Identifiers

PMID30099827
PMCPMC6172058
OpenAlexW2887280312

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.