Evidence map›Paper›PMID 30099739›Full record

ArticleImmunology2018

Human CD8 T-cell activation in acute and chronic chikungunya infection.

Cinthia Nóbrega de Sousa Dias, Bruna Macêdo Gois, Viviane Silva Lima, Isabel Cristina Guerra-Gomes, Josélio Maria Galvão Araújo, Juliana de Assis Silva Gomes, Demétrius Antônio Machado Araújo, Isac Almeida Medeiros, Fátima de Lourdes Assunção Araújo de Azevedo, Robson Cavalcanti Veras and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 29 citations in OpenAlex.

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  20. Chikungunya Virus Evades Antiviral CD8Journal of virology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Cinthia Nóbrega de Sousa DiasImmunology of Infectious Diseases Laboratory of Department of Cellular and Molecular Biology of Federal University of Paraíba, João Pessoa, Paraíba, Brazil.
Bruna Macêdo GoisImmunology of Infectious Diseases Laboratory of Department of Cellular and Molecular Biology of Federal University of Paraíba, João Pessoa, Paraíba, Brazil.
Viviane Silva LimaImmunology of Infectious Diseases Laboratory of Department of Cellular and Molecular Biology of Federal University of Paraíba, João Pessoa, Paraíba, Brazil.
Isabel Cristina Guerra-GomesImmunology of Infectious Diseases Laboratory of Department of Cellular and Molecular Biology of Federal University of Paraíba, João Pessoa, Paraíba, Brazil.
Josélio Maria Galvão AraújoMolecular Biology of Cancer and Infectious Diseases Laboratory of Post-Graduation Programme on Parasite Biology, Federal University of Rio Grande do Norte, Natal, Brazil.
Juliana de Assis Silva GomesDepartment of Morphology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Brazil.ORCID 0000-0002-8332-2907
Demétrius Antônio Machado AraújoDepartment of Biotechnology, Federal University of Paraiba, João Pessoa, Brazil.
Isac Almeida MedeirosResearch Institute for Drugs and Medicines, Federal University of Paraíba, João Pessoa, Brazil.
Fátima de Lourdes Assunção Araújo de AzevedoResearch Institute for Drugs and Medicines, Federal University of Paraíba, João Pessoa, Brazil.
Robson Cavalcanti VerasResearch Institute for Drugs and Medicines, Federal University of Paraíba, João Pessoa, Brazil.
Daniele Idalino JanebroImmunology of Infectious Diseases Laboratory of Department of Cellular and Molecular Biology of Federal University of Paraíba, João Pessoa, Paraíba, Brazil.
Ian Porto Gurgel do AmaralDepartment of Cellular and Molecular Biology, Federal University of Paraiba, João Pessoa, Brazil.
Tatjana Souza Lima KeesenImmunology of Infectious Diseases Laboratory of Department of Cellular and Molecular Biology of Federal University of Paraíba, João Pessoa, Paraíba, Brazil.ORCID 0000-0003-0964-389X
Universidade Federal da Paraíba · BRUniversidade Federal de Minas Gerais · BRUniversidade Federal do Rio Grande do Norte · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a need for more detailed elucidation of T-cell immunity in chikungunya infection. CD8 T cells are one of main actors against viruses. Here, we analysed CD8

Indexed as

Antigens, CDAntigens, Differentiation, T-LymphocyteCD69 AntigensCD8-Positive T-LymphocytesChikungunya FeverChikungunya virusCytokinesCytotoxicity, ImmunologicFas Ligand Proteinfas ReceptorGranzymesHumansInterleukin-10Interleukin-17Lectins, C-TypeLymphocyte ActivationAntigens, CDAntigens, Differentiation, T-LymphocyteCD69 AntigensCytokinesFas Ligand ProteinFAS protein, humanfas ReceptorGranzymesIL10 protein, humanIL17A protein, humanInterleukin-10Interleukin-17Lectins, C-TypeLysosomal-Associated Membrane Protein 1PerforinactivationCD8 T-cellchikungunya infectioncytokineshuman

Identifiers

PMID30099739
PMCPMC6231013
OpenAlexW2885741300

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.