Evidence map›Paper›PMID 30099629›Full record

ArticleCancer causes & control : CCC2018

Temporal reliability of serum soluble and endogenous secretory receptors for advanced glycation end-products (sRAGE and esRAGE) in healthy women.

Fen Wu, Yelena Afanasyeva, Anne Zeleniuch-Jacquotte, Jinghua Zhang, Ann Marie Schmidt, Yu Chen

Open access · greenAbstract read
In one paragraph

Article in Cancer causes & control : CCC, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Observational
  3. Review
  4. Observational
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Fen WuDepartment of Population Health, New York University School of Medicine, 650 1st Avenue, New York, NY, 10016, USA.
Yelena AfanasyevaDepartment of Population Health, New York University School of Medicine, 650 1st Avenue, New York, NY, 10016, USA.
Anne Zeleniuch-JacquotteDepartment of Population Health, New York University School of Medicine, 650 1st Avenue, New York, NY, 10016, USA.
Jinghua ZhangDepartment of Medicine, New York University School of Medicine, New York, NY, USA.
Ann Marie SchmidtDepartment of Medicine, New York University School of Medicine, New York, NY, USA.
Yu ChenDepartment of Population Health, New York University School of Medicine, 650 1st Avenue, New York, NY, 10016, USA. yu.chen@nyumc.org.ORCID http://orcid.org/0000-0002-1519-4894
New York University · US

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ADRIANA HEGUY · 1985 to 2026
$83.1M
RESEARCH IN ENVIRONMENTAL HEALTH SCIENCES (CENTER GRANT)P30ES000260 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI COSTA, MAX · 1985 to 2020
$26.1M
The NYU Women's Health StudyUM1CA182934 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ZELENIUCH-JAQUOTTE, ANNE · 2015 to 2019
$3.7M
National Cancer Institute P30 CA016087National Cancer Institute UM1CA182934National Institute of Environmental Health Sciences P30 ES000260NCI NIH HHS P30 CA016087NCI NIH HHS UM1 CA182934NIEHS NIH HHS P30 ES000260
6 · The paper itself

Abstract

purposeThe soluble receptor for advanced glycation end-products (sRAGE) and endogenous secretory RAGE (esRAGE) have been considered as biomarkers of several chronic diseases. However, the temporal reliability of their concentrations in the circulation is yet to be demonstrated. We evaluated whether a single measurement of serum sRAGE and esRAGE could serve as an estimate for usual serum levels in epidemiologic studies.

methodsSerum sRAGE and esRAGE were measured using ELISAs in three yearly samples from 36 participants in the New York University Women's Health Study. The intraclass correlation coefficient (ICC) was used to evaluate temporal reliability.

resultsThe intra- and inter-batch coefficients of variation were 3.0% and 14.8% for sRAGE and 6.5% and 34.7% for esRAGE, and decreased to 0.4% and 2.1% for sRAGE and 1.0% and 6.3% for esRAGE after log

conclusionOur results indicate that a single measurement of serum sRAGE and esRAGE is a sufficiently reliable measure of their usual levels that can be used in epidemiologic studies.

Indexed as

Enzyme-Linked Immunosorbent AssayBiomarkersFemaleHumansMiddle AgedNew YorkReceptor for Advanced Glycation End ProductsReproducibility of ResultsBiomarkersesRAGE protein, humanReceptor for Advanced Glycation End ProductsBiomarkerELISAEpidemiologyesRAGEReliabilitysRAGE

Identifiers

PMID30099629
PMCPMC6345555
OpenAlexW2885753783

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.