Evidence map›Paper›PMID 30099627›Full record

ArticleBrain topography2018

Electrophysiological Signatures of Intrinsic Functional Connectivity Related to rTMS Treatment for Mal de Debarquement Syndrome.

Yoon-Hee Cha, Guofa Shou, Diamond Gleghorn, Benjamin C Doudican, Han Yuan, Lei Ding

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain topography, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Transcranial Alternating Current Stimulation Reduces Network Hypersynchrony and Persistent Vertigo.Neuromodulation : journal of the International Neuromodulation Society · 2021
    Trial
  4. Article
  5. Article
  6. Article
  7. Review
  8. Transcranial Magnetic Stimulation as Treatment for Mal de Debarquement Syndrome: Case Report and Literature Review.Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology · 2020
    Article
  9. Occipital and Cerebellar Theta Burst Stimulation for Mal De Debarquement Syndrome.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2019
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yoon-Hee ChaLaureate Institute for Brain Research, 6655 South Yale Avenue, Tulsa, OK, 74136, USA. ycha@laureateinstitute.org.ORCID http://orcid.org/0000-0003-3804-0879
Guofa ShouStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK, USA.
Diamond GleghornLaureate Institute for Brain Research, 6655 South Yale Avenue, Tulsa, OK, 74136, USA.
Benjamin C DoudicanLaureate Institute for Brain Research, 6655 South Yale Avenue, Tulsa, OK, 74136, USA.
Han YuanLaureate Institute for Brain Research, 6655 South Yale Avenue, Tulsa, OK, 74136, USA.
Lei DingLaureate Institute for Brain Research, 6655 South Yale Avenue, Tulsa, OK, 74136, USA.
Laureate Institute for Brain Research · USUniversity of Oklahoma · US

Funding

The Center for Neuroscience-based Mental Health Assessment and Prediction (NEUROMAP)P20GM121312 · NIGMS · LAUREATE INSTITUTE FOR BRAIN RESEARCH · PI Masaya Misaki · 2017 to 2026
$23.7M
NIGMS NIH HHS P20 GM121312
6 · The paper itself

Abstract

To determine intrinsic functional connectivity (IFC) related to symptom changes induced by rTMS in mal de debarquement syndrome (MdDS), a motion perceptual disorder induced by entrainment to oscillating motion. Twenty right-handed women (mean age: 52.9 ± 12.6 years; mean duration illness: 35.2 ± 24.2 months) with MdDS received five sessions of rTMS (1 Hz right DLPFC, 10 Hz left DLPFC) over consecutive days. High-density (128-channel) resting-state EEG were recorded prior to and following treatment sessions and analyzed using a group-level independent component (IC) analysis. IFC between 19 ICs was quantified by inter-IC phase coherence (ICPC) in six frequency bands (delta, theta, low alpha, high alpha, beta, gamma). Correlational analyses between IFCs and symptoms were performed. Symptom improvement after rTMS was significantly correlated with (1) an increase in low alpha band (8-10 Hz) IFC but a decrease of IFC in all other bands, and (2) high baseline IFC in the high alpha (11-13 Hz) and beta bands (14-30 Hz). Most treatment related IFC changes occurred between frontal and parietal regions with a linear association between the degree of symptom improvement and the number of coherent IFC changes. Frequency band and region specific IFC changes correlate with and can predict symptom changes induced by rTMS over DLPFC in MdDS. MdDS symptom response correlates with high baseline IFC in most frequency bands. Treatment induced increase in long-range low alpha IFC and decreases in IFC in other bands as well as the proportion of coherent IFC changes correlate with symptom reduction.

Indexed as

Transcranial Magnetic StimulationTravel-Related IllnessAdultAgedElectroencephalographyFemaleFrontal LobeHumansMiddle AgedMotion PerceptionNeural PathwaysParietal LobePerceptual DisordersPrefrontal CortexVertigoEEGInter-independent component phase coherenceIntrinsic functional connectivityMal de debarquement syndromerTMS

Identifiers

PMID30099627
PMCPMC6182441
OpenAlexW2885256120

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.