Evidence map›Paper›PMID 30099097›Full record

ReviewNitric oxide : biology and chemistry2018

Signaling interplay between primary cilia and nitric oxide: A mini review.

Hannah C Saternos, Wissam A AbouAlaiwi

Abstract readReview
In one paragraph

Review in Nitric oxide : biology and chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Nitric oxide suppresses cilia activity in ctenophores.bioRxiv : the preprint server for biology · 2023
    Article
  5. Article
  6. Review
  7. Primary Cilia and Calcium Signaling Interactions.International journal of molecular sciences · 2020
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hannah C SaternosUniversity of Toledo, College of Pharmacy and Pharmaceutical Sciences, Department of Pharmacology and Experimental Therapeutics, USA.
Wissam A AbouAlaiwiUniversity of Toledo, College of Pharmacy and Pharmaceutical Sciences, Department of Pharmacology and Experimental Therapeutics, USA. Electronic address: Wissam.Abou-Alaiwi@UToledo.Edu.

Funding

Role of muscarinic receptor anatgonist in primary cilia structureR15HL140523 · NHLBI · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI ABOUALAIWI, WISSAM · 2018 to 2020
$601k
NHLBI NIH HHS R15 HL140523
6 · The paper itself

Abstract

New discoveries into the functional role of primary cilia are on the rise. In little more than 20 years, research has shown the once vestigial organelle is a signaling powerhouse involved in a vast number of essential cellular processes. In the same decade that interest in primary cilia was burgeoning, nitric oxide won molecule of the year and a Nobel prize for its role as a near ubiquitous signaling molecule. Although primary cilia and nitric oxide are both involved in signaling, a direct relationship has not been investigated; however, after a quick review of the literature, parallels between their functions can be drawn. This review aims to suggest a possible interplay between primary cilia and nitric oxide signaling especially in the areas of vascular tissue homeostasis and cellular proliferation.

Indexed as

AnimalsCell ProliferationCiliaDopamineHumansNitric OxideSignal TransductionVasodilationWound HealingDopamineNitric OxideNitric oxidePrimary ciliaSignaling

Identifiers

PMID30099097
PMCPMC6186180

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.