ArticleAmerican journal of ophthalmology2018
Conjunctival and Intrascleral Vasculatures Assessed Using Anterior Segment Optical Coherence Tomography Angiography in Normal Eyes.
Article in American journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.
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Who cites it
57 citing papers in PubMed, 1 synthesis or guideline pooled it, 112 citations in OpenAlex.
- Anterior Segment Optical Coherence Tomography and Anterior Segment Optical Coherence Tomography Angiography After Bleb Forming Glaucoma Surgeries: A Systematic Review.Clinical & experimental ophthalmology · 2025Pooled it
- Optical coherence tomography angiography in evaluating the response of ocular surface squamous neoplasia to topical immunotherapy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Circumferential multi-contrast mapping of the aqueous outflow pathway in human eyes facilitated by circular-scan optical coherence tomography angiography.Biomedical optics express · 2026Article
- Clinical Significance of Conjunctival Microvascular Density in Diabetic Retinopathy: A Multimodal Correlation Study Based on Swept-Source Optical Coherence Tomography Angiography.Journal of diabetes research · 2026Article
- Anterior segment optical coherence tomography angiography assessment of limbal vasculature changes after sclerocorneal vs. corneal cataract incisions.Scientific reports · 2025Article
- Investigation of conjunctival vasculature changes assessed by Anterior Segment Optical Coherence Tomography Angiography after photorefractive keratectomy: a pilot study.International ophthalmology · 2025Article
- Grading Scales of Conjunctival Inflammation.Diagnostics (Basel, Switzerland) · 2025Review
- Advanced imaging of corneal neovascularisation with a novel swept-source AS-OCTA system.The British journal of ophthalmology · 2025Observational
- Conjunctival and retinal microvascular loss in systemic lupus erythematosus: a swept-source OCTA study.Journal of translational medicine · 2025Article
- Correlation of Multimodal Clinical Imaging With the Whole-Slide- and Superresolution-Based Immunohistological Structure of the Corneal Limbal Stroma.Investigative ophthalmology & visual science · 2025Article
- PS-OCT imaging of the anterior segment under different eyeball rotations.Biomedical optics express · 2025Article
- Investigating the vascular structure of the conjunctiva in patients using spherical mini-scleral contact lenses utilizing OCT-A imaging.Scientific reports · 2025Article
- Anterior Segment Optical Coherence Tomography Angiography: A Review of Applications for the Cornea and Ocular Surface.Medicina (Kaunas, Lithuania) · 2024Review
- Impact of scleral cautery on limbal vasculature after cataract surgery assessed using optical coherence tomography angiography.Scientific reports · 2024Article
- Superficial ocular vascular changes after orbital decompression in patients with thyroid ophthalmopathy measured by anterior segment OCT angiography; an observational study.Scientific reports · 2024Observational
- Quantitative Characterization of Retinal Features in Translated OCTA.medRxiv : the preprint server for health sciences · 2024Article
- Quantitative characterization of retinal features in translated OCTA.Experimental biology and medicine (Maywood, N.J.) · 2024Article
- Qualitative and quantitative comparison of two semi-manual retinal vascular density analyzing methods on optical coherence tomography angiography images of healthy individuals.Scientific reports · 2023Article
- Current clinical applications of anterior segment optical coherence tomography angiography: a review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Review
- Anterior and posterior imaging with hyperparallel OCT.Biomedical optics express · 2023Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
purposeTo investigate conjunctival and intrascleral vasculatures using anterior segment optical coherence tomography angiography (AS-OCTA) in normal eyes.
designCross-sectional study.
methodsAS-OCTA images of the corneal limbus were acquired circumferentially using a swept-source optical coherence tomography system in 10 eyes of 10 healthy subjects. AS-OCTA flow patterns with en face maximum projection were compared between the superficial (from the conjunctival epithelium to a depth of 200 μm) and deep (from a depth of 200 μm to 1000 μm) layers. The OCTA images were also compared with fluorescein scleral angiography and indocyanine green aqueous angiography images. Quantitative parameters (vessel density, vessel length density, vessel diameter index, and fractal dimension) were compared among different locations.
resultsThe OCTA vessel patterns differed between the superficial and deep layers. The superficial-layer flow signals showed centrifugal patterns from the limbus, whereas the deep-layer flow signals showed segmental patterns. The OCTA en face images with whole signals had a similar appearance to the scleral angiography images, whereas those in the deep layer showed a similar appearance to the aqueous angiography images. In the superficial layer, only the vessel diameter index was significantly different among the locations (P = .003). In the deep layer, all 4 parameters differed significantly among the locations (P < .001 to P = .003).
conclusionsOCTA is a promising tool for evaluating conjunctival and intrascleral vasculatures. It may also help in understanding ocular surface blood flow relevant to vascular and ocular surface diseases, as well as aqueous humor outflow.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.