Evidence map›Paper›PMID 30098659›Full record

ReviewThe Psychiatric clinics of North America2018

Therapeutic Applications of Invasive Neuromodulation in Children and Adolescents.

Deniz Doruk Camsari, Melissa Kirkovski, Paul E Croarkin

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Psychiatric clinics of North America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. New Somatic Treatments for Child and Adolescent Depression.Current treatment options in psychiatry · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Deniz Doruk CamsariDepartment of Psychiatry and Psychology, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.
Melissa KirkovskiDeakin Child Study Centre, School of Psychology, Deakin University, Geelong, VIC 3220, Australia.
Paul E CroarkinDepartment of Psychiatry and Psychology, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA. Electronic address: croarkin.paul@mayo.edu.

Funding

Glutamatergic and GABAergic Biomarkers in rTMS for Adolescent DepressionR01MH113700 · NIMH · MAYO CLINIC ROCHESTER · PI CROARKIN, PAUL E · 2017 to 2021
$2.5M
Glutamate Probes in Adolescent DepressionK23MH100266 · NIMH · MAYO CLINIC ROCHESTER · PI CROARKIN, PAUL E · 2014 to 2017
$685k
NIMH NIH HHS K23 MH100266NIMH NIH HHS R01 MH113700
6 · The paper itself

Abstract

Although the application of noninvasive brain stimulation methods to children and adolescents has been frequently studied in depression, autism spectrum disorder, attention-deficit/hyperactivity disorder, and other neuropsychiatric disorders, invasive methods such as deep brain stimulation (DBS) and vagal nerve stimulation (VNS) have received less attention. DBS and VNS have demonstrated utility in young patients especially for dystonia and epilepsy. VNS has FDA clearance for intractable epilepsy in patients aged 4 years and older. Further measured work with invasive neuromodulation for children and adolescents with debilitating neuropsychiatric disorders could provide new treatment options and expand current knowledge base of neurocircuitry across development.

Indexed as

AdolescentChildDeep Brain StimulationDrug Resistant EpilepsyDystoniaHumansObsessive-Compulsive DisorderTourette SyndromeVagus Nerve StimulationAdolescentsChildrenDBSDeep brain stimulationInvasive brain stimulationNeuromodulationVagal nerve stimulationVNS

Identifiers

PMID30098659
PMCPMC6092040

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.