ArticleThe journal of pain2019
Associations Between Adolescent Chronic Pain and Prescription Opioid Misuse in Adulthood.
Article in The journal of pain, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05774002 (Psychological Assessment of Scoliosis Patients Undergoing Surgical Management), which is not on this map. Cited by 66 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Psychological Assessment of Scoliosis Patients Undergoing Surgical Management (PASS)
Who cites it
66 citing papers in PubMed, 1 synthesis or guideline pooled it, 129 citations in OpenAlex.
- Systematic review of the use of prescription and non-prescription psychotropic drugs and their relation with mental health in university population.Frontiers in psychology · 2025Pooled it
- Examining changes in pain interference via pandemic-induced isolation among patients receiving medication for opioid use disorder: a secondary data analysis.BMC public health · 2024Trial
- Trauma exposure across the lifespan among individuals engaged in treatment with medication for opioid use disorder: differences by gender, PTSD status, and chronic pain.Substance abuse treatment, prevention, and policy · 2024Trial
- Medical Diagnosis, ED Visits, and Hospitalizations for Substance Use in U.S. Children's Hospitals: A Retrospective Multi-Center Cohort Study.Children (Basel, Switzerland) · 2026Article
- Prescription Opioid Misuse Among High School Athletes During the Opioid Prescribing Limit Law Era: YRBSS 2017-2023.Healthcare (Basel, Switzerland) · 2026Article
- Adolescent pain reports share genetic overlap with adult chronic pain conditions: A polygenic score analysis using the ABCD study.The journal of pain · 2026Article
- Adolescent outcomes of Post-operative opioid EXposure (APEX): Protocol for a multisite observational study.Journal of substance use and addiction treatment · 2026Article
- Cortical thickness, surface area, and multisite pain: distinct patterns by sex in adolescence.Biology of sex differences · 2026Article
- Longitudinal Associations Among Pain Catastrophizing, Pain Interference, and Pain Medication Use in Adolescents With Chronic Pain.European journal of pain (London, England) · 2026Article
- Genetic and Environmental Associations Among Pain, Sleep Disturbances, and Substance Use Intent in Early Adolescence.Journal of adolescence · 2026Article
- The emergence of sex differences in primary pain during adolescence: a conceptual developmentally-oriented biopsychosocial model and opportunities for further investigation.BMC pediatrics · 2025Review
- Digital health solutions for caregivers of children experiencing acute pain: a scoping review.Pain reports · 2025Review
- Parental Diseases of Despair and Suicidal Events in Their Children.JAMA network open · 2025Article
- Optimizing psychological treatments for pediatric chronic pain to enhance outcomes, availability, and accessibility.Current opinion in psychology · 2025Review
- Balancing Care and Sacrifice: Lived Experiences and Support Needs of Primary Caregivers in Pediatric Chronic Pain Across Canada and Australia.Children (Basel, Switzerland) · 2025Article
- Exploring academic achievement and relevant risk factors among a community sample of adolescents with chronic pain compared to peers.Journal of pediatric psychology · 2025Article
- Extended Reality (XR) in Pediatric Acute and Chronic Pain: Systematic Review and Evidence Gap Map.JMIR pediatrics and parenting · 2025Review
- Article
- Racial and sex disparities in inpatient outcomes of patients with opioid overdose: a nationwide analysis.Proceedings (Baylor University. Medical Center) · 2025Article
- Coping in youth living with chronic pain: A systematic review of qualitative evidence.Canadian journal of pain = Revue canadienne de la douleur · 2025Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Prescription opioid misuse is a serious public health concern, yet antecedent factors are poorly described. Using data from the National Longitudinal Study of Adolescent to Adult Health (N = 14,784), we examined the longitudinal relationship between a history of adolescent chronic pain and the odds of misusing prescription opioids in adulthood. The primary predictor variable was chronic pain status during adolescence. The primary outcome variables were prescription opioid misuse during early adulthood and adulthood. Multivariate models controlled for known risk factors of opioid misuse, including sociodemographics (sex, race, and ethnicity), adolescent mental health symptoms (anxiety, depression), adolescent self-reported physical health status, adolescent substance use/abuse, childhood trauma, and adult legitimate opioid use. We found that adults with a history of adolescent chronic pain were more likely to misuse opioids than those without history of chronic pain, even after controlling for other known risk factors. Further, we found that among individuals with history of adolescent chronic pain that race (white), other substance use, and exposure to trauma were risk factors for later opioid misuse. Longitudinal associations between adolescent chronic pain and subsequent adult prescription opioid misuse highlight the need for early targeted screening and prevention efforts that may reduce later opioid misuse. Perspective: Using a large, nationally representative sample, we found that chronic pain during adolescence was an independent risk factor for opioid misuse in adulthood, over and above other known risk factors. Furthermore, among those individuals with adolescent chronic pain, substance use, exposure to trauma, and race were associated with opioid misuse.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.