Evidence map›Paper›PMID 30098317›Full record

ReviewJournal of immunological methods2018

Measuring immune responses to pneumococcal vaccines.

David C LaFon, Moon H Nahm

Open access · greenAbstract readReview
In one paragraph

Review in Journal of immunological methods, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 61 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

David C LaFonDivision of Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Moon H NahmDivision of Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA; Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA. Electronic address: mnahm@uabmc.edu.
University of Alabama at Birmingham · US

Funding

Training Program in Lung Biology and Translational MedicineT32HL105346 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GAGGAR, AMIT · 2010 to 2025
$5.0M
Acquired deficiency of innate immunity (ficolin-2) among elderly adultsR01AG050607 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI NAHM, MOON H. · 2015 to 2019
$1.6M
NHLBI NIH HHS T32 HL105346NIAID NIH HHS HHSN272201200005CNIAID NIH HHS N01 AI030021NIA NIH HHS R01 AG050607
6 · The paper itself

Abstract

Quantitative assays that measure immune response to pneumococcal vaccines are not only important for the evaluation of vaccine immunogenicity and efficacy, but are also utilized in the clinical diagnosis of immune deficiency syndromes. Analytical methods have progressed in order to meet changing demands in both of these areas, from early methods to ELISA, and most recently multiplex bead array assays and opsonophagocytosis assays (OPA). It is necessary to understand the evolution of such techniques and the criteria for their interpretation in order to better inform the application of currently available methods, and to guide future investigation into assay development.

Indexed as

Adaptive ImmunityAntibodies, BacterialImmunologic Deficiency SyndromesPneumococcal VaccinesEnzyme-Linked Immunosorbent AssayHumansAntibodies, BacterialPneumococcal VaccinesImmune deficiencyImmune responsePneumococcalStreptococcus pneumoniaeVaccine

Identifiers

PMID30098317
PMCPMC6169307
OpenAlexW2887374603

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.