ArticleWound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society2018
Role of Schwann cells in cutaneous wound healing.
Article in Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 34 citations in OpenAlex.
- Biomimetic Dermal Substitutes for Skin Reconstruction: Advances in Scaffold Design, Biological Integration, and Clinical Performance.Journal of functional biomaterials · 2026Review
- Axonal regeneration and hyperglycemia in wound healing: a review on the role of activin A, TNFRSF10B, and Synaptophysin.Molecular biology reports · 2026Review
- Spatiotemporal dynamics of mammalian wound healing.Cell discovery · 2026Review
- Pathologic and Therapeutic Schwann Cells.Cells · 2025Review
- Alteration of skin fibroblast steady state contributes to healing outcomes.bioRxiv : the preprint server for biology · 2024Article
- The transcriptional profile of keloidal Schwann cells.Experimental & molecular medicine · 2022Article
- Identification of early biomarkers in saliva in genetically engineered mouse model C(3)1-TAg of breast cancer.Scientific reports · 2022Article
- Glioma Pericytes Promote Angiogenesis by Producing Periostin.Cellular and molecular neurobiology · 2022Review
- Diminished schwann cell repair responses play a role in delayed diabetes-associated wound healing.Frontiers in physiology · 2022Article
- Circulating Nestin-GFPStem cell reviews and reports · 2021Article
- Sensory nerves in the spotlight of the stem cell niche.Stem cells translational medicine · 2021Review
- Review
- Neural stem cell niche heterogeneity.Seminars in cell & developmental biology · 2019Review
- Skeletal Stem Cell-Schwann Cell Circuitry in Mandibular Repair.Cell reports · 2019Article
- Staphylococcus epidermidis role in the skin microenvironment.Journal of cellular and molecular medicine · 2019Article
- Pericytes Act as Key Players in Spinal Cord Injury.The American journal of pathology · 2019Review
- Pericyte Plasticity in the Brain.Neuroscience bulletin · 2019Review
- Cross-talk between lung cancer and bones results in neutrophils that promote tumor progression.Cancer metastasis reviews · 2018Review
- Promyelocytic leukemia protein in mesenchymal stem cells is essential for leukemia progression.Annals of hematology · 2018Review
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
Dermal wound healing is the process of repairing and remodeling skin following injury. Delayed or aberrant cutaneous healing poses a challenge for the health care system. The lack of detailed understanding of cellular and molecular mechanisms involved in this process hampers the development of effective targeted treatments. In a recent study, Parfejevs et al.-using state-of-the-art technologies, including in vivo sophisticated Cre/loxP techniques in combination with a mouse model of excisional cutaneous wounding-reveal that Schwann cells induce adult dermal wound healing. Strikingly, genetic ablation of Schwann cells delays wound contraction and closure, decreases myofibroblast formation, and impairs skin re-epithelization after injury. From a drug development perspective, Schwann cells are a new cellular candidate to be activated to accelerate skin healing. Here, we summarize and evaluate recent advances in the understanding of Schwann cells roles in the skin microenvironment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.