Evidence map›Paper›PMID 30098119›Full record

ArticleJournal of biophotonics2019

Spectral correction for handheld optoacoustic imaging by means of near-infrared optical tomography in reflection mode.

Leonie Ulrich, Linda Ahnen, Hidayet Günhan Akarçay, Salvador Sánchez Majos, Michael Jaeger, Kai Gerrit Held, Martin Wolf, Martin Frenz

Abstract read
In one paragraph

Article in Journal of biophotonics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Leonie UlrichInstitute of Applied Physics, University of Bern, Bern, Switzerland.
Linda AhnenBiomedical Optics Research Laboratory, Department of Neonatology, University Hospital Zurich, Zurich, Switzerland.
Hidayet Günhan AkarçayInstitute of Applied Physics, University of Bern, Bern, Switzerland.
Salvador Sánchez MajosBiomedical Optics Research Laboratory, Department of Neonatology, University Hospital Zurich, Zurich, Switzerland.
Michael JaegerInstitute of Applied Physics, University of Bern, Bern, Switzerland.
Kai Gerrit HeldInstitute of Applied Physics, University of Bern, Bern, Switzerland.
Martin WolfBiomedical Optics Research Laboratory, Department of Neonatology, University Hospital Zurich, Zurich, Switzerland.
Martin FrenzInstitute of Applied Physics, University of Bern, Bern, Switzerland.ORCID 0000-0002-6741-9434

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In vivo imaging of tissue/vasculature oxygen saturation levels is of prime interest in many clinical applications. To this end, the feasibility of combining two distinct and complementary imaging modalities is investigated: optoacoustics (OA) and near-infrared optical tomography (NIROT), both operating noninvasively in reflection mode. Experiments were conducted on two optically heterogeneous phantoms mimicking tissue before and after the occurrence of a perturbation. OA imaging was used to resolve submillimetric vessel-like optical absorbers at depths up to 25 mm, but with a spectral distortion in the OA signals. NIROT measurements were utilized to image perturbations in the background and to estimate the light fluence inside the phantoms at the wavelength pair (760 nm, 830 nm). This enabled the spectral correction of the vessel-like absorbers' OA signals: the error in the ratio of the absorption coefficient at 830 nm to that at 760 nm was reduced from 60%-150% to 10%-20%. The results suggest that oxygen saturation (SO

Indexed as

Infrared RaysOptical PhenomenaCalibrationImage Processing, Computer-AssistedPhantoms, ImagingPhotoacoustic TechniquesSignal-To-Noise RatioTomography, Opticalblood oxygen saturationfluence compensationmultimodal imagingnear-infrared optical tomographyoptoacoustic signal quantificationquantitative optoacoustic imagingspectral correction

Identifiers

PMID30098119
PMCPMC7065640

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.