Evidence map›Paper›PMID 30098062›Full record

ArticleMolecular microbiology2018

Rhodobacterales use a unique L-threonine kinase for the assembly of the nucleotide loop of coenzyme B

Norbert K Tavares, Chelsey M VanDrisse, Jorge C Escalante-Semerena

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. TheiScience · 2024
    Article
  2. Review
  3. Review
  4. Biosynthesis of the modified tetrapyrroles-the pigments of life.The Journal of biological chemistry · 2020
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Norbert K TavaresDepartment of Microbiology, University of Georgia, Athens, GA, USA.ORCID 0000-0002-4989-1620
Chelsey M VanDrisseDepartment of Microbiology, University of Georgia, Athens, GA, USA.ORCID 0000-0001-9139-0443
Jorge C Escalante-SemerenaDepartment of Microbiology, University of Georgia, Athens, GA, USA.ORCID 0000-0001-7428-2811
University of Georgia · US

Funding

Request for a supplement for equipmentR37GM040313 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI ESCALANTE, JORGE C · 2010 to 2018
$3.5M
Membrane-associated Steps in Coenzyme B12 BiosynthesisF31GM095230 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI TAVARES, NORBERT K · 2011 to 2014
$169k
NIGMS NIH HHS F31 GM095230NIGMS NIH HHS R37 GM040313
6 · The paper itself

Abstract

Several of the enzymes involved in the conversion of adenosylcobyric acid (AdoCby) to adenosylcobamide (AdoCba) are yet to be identified and characterized in some cobamide (Cba)-producing prokaryotes. Using a bioinformatics approach, we identified the bluE gene (locus tag RSP_0788) of Rhodobacter sphaeroides 2.4.1 as a putative functional homolog of the L-threonine kinase enzyme (PduX, EC 2.7.1.177) of S. enterica. In AdoCba, (R)-1-aminopropan-2-ol O-phosphate (AP-P) links the nucleotide loop to the corrin ring; most known AdoCba producers derive AP-P from L-Thr-O-3-phosphate (L-Thr-P). Here, we show that RsBluE has L-Thr-independent ATPase activity in vivo and in vitro. We used

Indexed as

Amino Acid SequenceBacterial ProteinsCobaltCobamidesNucleotidesPhylogenyProtein Serine-Threonine KinasesRhodobacter capsulatusRhodobacter sphaeroidesSalmonella entericaSerineThreonineBacterial ProteinsCobaltCobamidesNucleotidesProtein Serine-Threonine KinasesSerineThreonine

Identifiers

PMID30098062
PMCPMC6195846
OpenAlexW2885621402

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.