Evidence map›Paper›PMID 30098061›Full record

GuidelineJournal of the European Academy of Dermatology and Venereology : JEADV2018

MelaNostrum: a consensus questionnaire of standardized epidemiologic and clinical variables for melanoma risk assessment by the melanostrum consortium.

Alexander J Stratigos, Maria Concetta Fargnoli, Arcangela De Nicolo, Ketty Peris, Susana Puig, Efthymia Soura, Chiara Menin, Donato Calista, Paola Ghiorzo, Mario Mandala and 10 more

Open access · bronzeAbstract readPractice Guideline
In one paragraph

Guideline in Journal of the European Academy of Dermatology and Venereology : JEADV, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 15 institutions in 6 countries.

Alexander J StratigosFirst Department of Dermatology, National and Kapodistrian University of Athens School of Medicine, Andreas Sygros Hospital, Athens, Greece.
Maria Concetta FargnoliDepartment of Dermatology, University of L'Aquila, L'Aquila, Italy.
Arcangela De NicoloCancer Genomics Program, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy.
Ketty PerisInstitute of Dermatology, Catholic University, Rome, Italy.
Susana PuigDermatology Department, Melanoma Unit, Hospital Clinic de Barcelona, Universitat de Barcelona, Barcelona, Spain.
Efthymia SouraFirst Department of Dermatology, National and Kapodistrian University of Athens School of Medicine, Andreas Sygros Hospital, Athens, Greece.
Chiara MeninImmunology and Diagnostic Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy.
Donato CalistaDermatology Unit, Maurizio Bufalini Hospital, Cesena, Italy.
Paola GhiorzoDepartment of Internal Medicine and Medical Specialties, University of Genoa and Genetics of Rare Cancers, University Hospital Policlinico San Martino-IRCCS, Genoa, Italy.
Mario MandalaUnit of Melanoma, Department of Oncology and Hematology, Papa Giovanni XXIII Cancer Center Hospital, Bergamo, Italy.
Daniela MassiDepartment of Surgery and Translational Medicine, University of Florence, Florence, Italy.
Monica RodolfoImmunotherapy Unit, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Laura Del RegnoInstitute of Dermatology, Catholic University, Rome, Italy.
Irene StefanakiFirst Department of Dermatology, National and Kapodistrian University of Athens School of Medicine, Andreas Sygros Hospital, Athens, Greece.
Helen GogasDepartment of Internal Medicine, Laikon Hospital, National and Kapodistrian University of Athens School of Medicine, Athens, Greece.
Veronique BatailleDepartment of Twin Research and Genetic Epidemiology, Kings College, London, UK.
Margaret A TuckerHuman Genetics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
David WhitemanPopulation Health Department, QIMR Berghofer Medical Research Institute, Brisbane, Qld, Australia.
Eduardo NagoreDepartment of Dermatology, Instituto Valenciano de Oncología, València, Spain.
Maria Teresa LandiHuman Genetics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
National and Kapodistrian University of Athens · GRIstituto Oncologico Veneto · ITAndreas Sygros Hospital · GRFondazione IRCCS Istituto Nazionale dei Tumori · ITFundación Instituto Valenciano de Oncología · ESHospital Clínic de Barcelona · ESKing's College London · GBNational Cancer Institute · USNational Institutes of Health · USOspedale “M. Bufalini” di Cesena · ITOspedale Papa Giovanni XXIII · ITQIMR Berghofer Medical Research Institute · AUUniversity of Florence · ITUniversity of Genoa · ITUniversity of L'Aquila · IT

Funding

Family Studies ZIACP004410 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI SAVAGE, SHARON A. · 2009 to 2025
$56.1M
Studies of Genetic and Environmental EpidemiologyZIACP101231 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI LANDI, MARIA · 2018 to 2025
$23.6M
STUDIES OF PERSONS AT HIGH RISK OF CANCER--GENETIC EPIDEMIOLOGYZ01CP004410 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI TUCKER, MARGARET · 1985 to 2008
$15.0M
SUBTHRESHOLD MUSCLE AFFERENT INPUT TO DORSAL HORNF06TW002012 · FIC · UNIVERSITY OF CALIFORNIA DAVIS · PI KAUFMAN, MARC PETER · 1995 to 1995
–
European Commission under the 6th Framework Programme LSHC-CT-2006-018702European Development Regional Fund AGAUR 2014_SGR_603Fundación Científica de la Asociación Española Contra el Cáncer GCB15152978SOENIntramural NIH HHS Z01 CP004410Intramural NIH HHS ZIA CP101231Italian Ministry of Health AIRC IG 15460Italian Ministry of the University and Scientific Research 2012JJX494Italian Ministry of the University and Scientific Research PRIN-2012NCI NIH HHSNIHSpanish Fondo de Investigaciones Sanitarias PI15/00716Spanish Fondo de Investigaciones Sanitarias PI15/00956
6 · The paper itself

Abstract

backgroundMany melanoma observational studies have been carried out across different countries and geographic areas using heterogeneous assessments of epidemiologic risk factors and clinical variables.

aimTo develop a consensus questionnaire to standardize epidemiologic and clinical data collection for melanoma risk assessment.

methodsWe used a stepwise strategy that included: compilation of variables from case-control datasets collected at various centres of the MelaNostrum Consortium; integration of variables from published case-control studies; consensus discussion of the collected items by MelaNostrum members; revision by independent experts; addition of online tools and image-based charts; questionnaire testing across centres and generation of a final draft.

resultsWe developed a core consensus questionnaire (MelanoQ) that includes four separate sections: A. general and demographic data; B. phenotypic and ultraviolet radiation exposure risk factors and lifestyle habits; C. clinical examination, medical and family history; and D. diagnostic data on melanoma (cases only). Accompanying online tools, informative tables, and image-based charts aid standardization. Different subsections of the questionnaire are designed for self-administration, patient interviews performed by a physician or study nurse, and data collection from medical records.

conclusionsThe MelanoQ questionnaire is a useful tool for the collection and standardization of epidemiologic and clinical data across different studies, centres, cultures and languages. This will expedite ongoing efforts to compile high-quality data for pooled analyses or meta-analyses and offer a solid base for the design of clinical, epidemiologic and translational studies on melanoma.

Indexed as

MelanomaSkin NeoplasmsSurveys and QuestionnairesEpidemiologic MethodsHumansLife StyleMedical History TakingRadiation ExposureRisk AssessmentUltraviolet Rays

Identifiers

PMID30098061
PMCPMC7100361
OpenAlexW2887801933

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.