Evidence map›Paper›PMID 30098009›Full record

ArticleFEBS letters2018

Consequences of Cre-mediated deletion of Ciz1 exon 5 in mice.

Jianfeng Xiao, Mohammad Moshahid Khan, Satya Vemula, Jun Tian, Mark S LeDoux

Abstract read
In one paragraph

Article in FEBS letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Jianfeng XiaoDepartments of Neurology, and Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN, USA.
Mohammad Moshahid KhanDepartments of Neurology, and Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN, USA.ORCID 0000-0003-4679-294X
Satya VemulaDepartments of Neurology, and Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN, USA.
Jun TianDepartments of Neurology, and Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN, USA.
Mark S LeDouxDepartments of Neurology, and Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN, USA.ORCID 0000-0002-1748-3390
University of Tennessee Health Science Center · US

Funding

Genetics and Biology of CIZ1 in Cervical DystoniaR01NS082296 · NINDS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI LEDOUX, MARK S · 2013 to 2016
$1.3M
The Role of THAP1 in DystoniaR01NS069936 · NINDS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI LEDOUX, MARK S · 2010 to 2013
$1.3M
The Role of UBTF in Undiagnosed Neurodevelopmental DisordersR21GM118962 · NIGMS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI HORI, RODERICK T · 2016 to 2017
$456k
Pathophysiology of Paroxysmal DyskinesiasR56NS094965 · NINDS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI LEDOUX, MARK S · 2017 to 2017
$438k
Mouse Models of Paroxysmal Non-kinesigenic DyskinesiaR03NS101485 · NINDS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI XIAO, JIANFENG · 2018 to 2019
$152k
NIGMS NIH HHS R21 GM118962NINDS NIH HHS R01 NS069936NINDS NIH HHS R01 NS082296NINDS NIH HHS R03 NS101485NINDS NIH HHS R56 NS094965
6 · The paper itself

Abstract

CIZ1 plays a role in DNA synthesis at the G1/S checkpoint. Ciz1 gene-trap null mice manifest motor dysfunction, cell-cycle abnormalities, and DNA damage. In contrast, it has previously been reported that mouse embryonic fibroblasts derived from presumed Ciz1 knock-out mice (Ciz1

Indexed as

DNA DamageAnimalsCell CycleCells, CulturedEmbryo, MammalianExonsFemaleFibroblastsIntegrasesMaleMice, Inbred C57BLMice, KnockoutMice, TransgenicMotor ActivityNuclear ProteinsCiz1 protein, mouseCre recombinaseIntegrasesNuclear ProteinscerebellumCIZ1dystoniafloxedRNA-Seq

Identifiers

PMID30098009
PMCPMC6275157
OpenAlexW2886923612

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.