Evidence map›Paper›PMID 30097968›Full record

ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2019

Technical Aspects of Orthotopic Liver Transplantation-a Survey-Based Study Within the Eurotransplant, Swisstransplant, Scandiatransplant, and British Transplantation Society Networks.

Zoltan Czigany, Marcus N Scherer, Johann Pratschke, Markus Guba, Silvio Nadalin, Arianeb Mehrabi, Gabriela Berlakovich, Xavier Rogiers, Jacques Pirenne, Jan Lerut and 9 more

Open access · greenAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Guideline
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  10. Low Postoperative Platelet Counts Are Associated with Major Morbidity and Inferior Survival in Adult Recipients of Orthotopic Liver Transplantation.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 14 institutions in 7 countries.

Zoltan CziganyDepartment of Surgery and Transplantation, University Hospital RWTH Aachen, Pauwelsstrasse 30, Aachen, 52074, Germany.
Marcus N SchererDepartment of Surgery and Transplantation, University Hospital Regensburg, Regensburg, Germany.
Johann PratschkeDepartment of Surgery and Transplantation, University Hospital Berlin - Charité, Berlin, Germany.
Markus GubaDepartment of Surgery, University Hospital Munich, Munich, Germany.
Silvio NadalinDepartment of Surgery and Transplantation, University Hospital Tuebingen, Tuebingen, Germany.
Arianeb MehrabiDepartment of General, Visceral and Transplant Surgery, University of Heidelberg, Heidelberg, Germany.
Gabriela BerlakovichDepartment of Surgery, Division of Transplantation, Medical University of Vienna, Vienna, Austria.
Xavier RogiersDepartment of Solid Organ Transplantation, University Hospital Gent, Ghent, Belgium.
Jacques PirenneDepartment of Hepatobiliary Surgery and Transplantation, University Hospital Leuven, Leuven, Belgium.
Jan LerutUnit of Liver Transplantation and General Surgery, University Hospitals St.-Luc, Brussels, Belgium.
Zoltan MatheDepartment of Surgery and Transplantation, Semmelweis University, Budapest, Hungary.
Philipp DutkowskiDepartment of Surgery and Transplantation, University Hospital Zurich, Zurich, Switzerland.
Bo-Göran EriczonDepartment of Solid Organ Transplantation, University Hospital Stockholm - Karolinska Institute, Stockholm, Sweden.
Massimo MalagóDepartment of Hepatobiliary Surgery and Transplantation, University College London, London, UK.
Nigel HeatonDepartment of Hepatobiliary Surgery and Transplantation, King's College Hospital, London, UK.
Wenzel SchöningDepartment of Surgery and Transplantation, University Hospital RWTH Aachen, Pauwelsstrasse 30, Aachen, 52074, Germany.
Jan BednarschDepartment of Surgery and Transplantation, University Hospital RWTH Aachen, Pauwelsstrasse 30, Aachen, 52074, Germany.
Ulf Peter NeumannDepartment of Surgery and Transplantation, University Hospital RWTH Aachen, Pauwelsstrasse 30, Aachen, 52074, Germany.
Georg LurjeDepartment of Surgery and Transplantation, University Hospital RWTH Aachen, Pauwelsstrasse 30, Aachen, 52074, Germany. glurje@ukaachen.de.ORCID 0000-0001-9674-0756
RWTH Aachen University · DECharité - Universitätsmedizin Berlin · DEGhent University Hospital · BEHeidelberg University · DEKarolinska University Hospital · SEKing's College Hospital · GBKU Leuven · BELMU Klinikum · DEMedical University of Vienna · ATSemmelweis University · HUUniversitätsklinikum Aachen · DEUniversity College London · GBUniversity Hospital of Zurich · CHUniversity Hospital Regensburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOrthotopic liver transplantation (OLT) has emerged as the mainstay of treatment for end-stage liver disease. However, technical aspects of OLT are still subject of ongoing debate and are widely based on personal experience and local institutional protocols.

methodsAn international online survey was sent out to all liver transplant centers (n = 52) within the Eurotransplant, Swisstransplant, Scandiatransplant, and British Transplant Society networks. The survey sought information on center-specific OLT caseload, vascular and biliary reconstruction, graft reperfusion, intraoperative control of hemodynamics, and drain policies.

resultsForty-two centers gave a valid response (81%). Out of these, 50% reported piggy-back and 40.5% total caval replacement as their standard technique. While 48% of all centers generally do not apply veno-venous bypass (vvBP) or temporary portocaval shunt (PCS) during OLT, vvBP/PCS are routinely used in six centers (14%). Portal vein first reperfusion is used in 64%, followed by simultaneous (17%), and retrograde reperfusion (12%). End-to-end duct-to-duct anastomosis without biliary drain (67%) is the most frequently performed method of biliary reconstruction. No significant associations were found between the center caseload and the surgical approach used. The predominant part of the centers (88%) stated that techniques of OLT are not evidence-based and 98% would participate in multicenter clinical trials on these topics.

conclusionTechnical aspects of OLT vary widely among European centers. The extent to which center-specific variation of techniques affect transplant outcomes in Europe should be elucidated further in prospective multicenter trials.

Indexed as

Societies, MedicalEnd Stage Liver DiseaseEuropeFemaleHumansLiver TransplantationMalePortacaval Shunt, SurgicalProspective StudiesRetrospective StudiesAbdominal drainLiver transplantationPiggy-backReperfusionSurvey

Identifiers

PMID30097968
OpenAlexW2765646052

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.