Evidence map›Paper›PMID 30097964›Full record

ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2019

Factors Associated with Long-Term Quality of Life After Restorative Proctocolectomy with Ileal Pouch Anal Anastomosis.

Olga A Lavryk, Luca Stocchi, Tracy L Hull, Emre Gorgun, Sherief Shawki, Jeremy M Lipman, Stefan D Holubar, Conor P Delaney, Scott R Steele

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Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Peristaltic contractility: another factor impacting IPAA function?International journal of colorectal disease · 2025
    Observational
  3. Article
  4. Crohn's of the Pouch: Now What?Clinics in colon and rectal surgery · 2022
    Review
  5. Clinical Discrimination of Chronic Pouchitis After Ileal Pouch-Anal Anastomosis in Patients with Ulcerative Colitis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Olga A LavrykDepartment of Colorectal Surgery, Cleveland Clinic, Cleveland, OH, 44195, USA.ORCID 0000-0001-6779-785X
Luca StocchiDepartment of Colorectal Surgery, Cleveland Clinic, Cleveland, OH, 44195, USA.
Tracy L HullDepartment of Colorectal Surgery, Cleveland Clinic, Cleveland, OH, 44195, USA.
Emre GorgunDepartment of Colorectal Surgery, Cleveland Clinic, Cleveland, OH, 44195, USA.
Sherief ShawkiDepartment of Colorectal Surgery, Cleveland Clinic, Cleveland, OH, 44195, USA.
Jeremy M LipmanDepartment of Colorectal Surgery, Cleveland Clinic, Cleveland, OH, 44195, USA.
Stefan D HolubarDepartment of Colorectal Surgery, Cleveland Clinic, Cleveland, OH, 44195, USA.
Conor P DelaneyDepartment of Colorectal Surgery, Cleveland Clinic, Cleveland, OH, 44195, USA.
Scott R SteeleDepartment of Colorectal Surgery, Cleveland Clinic, Cleveland, OH, 44195, USA. steeles3@ccf.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

THE

aimThe aim of this study was to analyze factors associated with quality of life (QoL) after ileal pouch anal anastomosis (IPAA).

methodsPatients who underwent IPAA (1983-2015) and replied to QoL questionnaire were identified from an IRB-approved prospectively maintained IPAA-database. QoL was assessed using Cleveland Global Quality of Life (CGQL) questionnaire at 1, 3, 5, and 10 years postoperatively. Patient cohort was divided in two groups: overall QoL score ≤ 0.7 (low) and > 0.7 (high). Demographics, perioperative morbidity, and functional results were analyzed.

resultsA total of 4059 patients replied to the questionnaire at the most recent follow-up and were included. A total of 2889 (71%) had overall QoL > 0.7 (group 1) and 1170 (29%) patients had overall QoL ≤ 0.7 (group 2). Patients in group 1 had lower rates of early (44.6 vs. 50.4%, p = 0.003) and late (55.7 vs. 64.5%, p < 0.003) postoperative complications. Kaplan-Meier survival analysis demonstrated significantly higher rates of pouch failure among patients with lower QoL. Pouchitis, obstruction, fistulas, higher number of stools, and IPAA performed during the most recent decade (2005-2015) were significantly associated with lower QoL (≤ 0.7), while S-pouch configuration was associated with higher QoL (> 0.7).

conclusionPatient's characteristics and minimal perioperative complications impact patient's QoL following IPAA not only in the short term, but also in the long term.

Indexed as

ForecastingQuality of LifeAdultFemaleFollow-Up StudiesHumansIncidenceMalePostoperative ComplicationsProctocolectomy, RestorativeRisk FactorsSurveys and QuestionnairesUnited StatesIleal pouch anal anastomosisInflammatory bowel diseaseQuality of life

Identifiers

PMID30097964

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.