Evidence map›Paper›PMID 30097797›Full record

ArticleImmunologic research2018

Immunization with Chlamydia psittaci plasmid-encoded protein CPSIT_p7 induces partial protective immunity against chlamydia lung infection in mice.

Yuan Tan, Yumeng Li, Yang Zhang, Jian Yu, Yating Wen, Chuan Wang, Man Xu, Qian Chen, Chunxue Lu, Yimou Wu

Open access · bronzeAbstract read
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In one paragraph

Article in Immunologic research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Intestinal IL-22RA1 signaling regulatesFrontiers in microbiology · 2025
    Article
  4. Examining the effect of activated cytotoxic (CD8Medical oncology (Northwood, London, England) · 2023
    Article
  5. Protective Immunity againstInternational journal of molecular sciences · 2023
    Article
  6. Article
  7. Efficacy of Pgp3 vaccination forFrontiers in immunology · 2022
    Article
  8. Frontiers in microbiology · 2020
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yuan TanInstitution of Pathogenic Biology, Medical College, University of South China, Hengyang, 421001, China.
Yumeng LiInstitution of Pathogenic Biology, Medical College, University of South China, Hengyang, 421001, China.
Yang ZhangDepartment of Pathology, University of South China, Hengyang, 421001, China.
Jian YuInstitution of Pathogenic Biology, Medical College, University of South China, Hengyang, 421001, China.
Yating WenInstitution of Pathogenic Biology, Medical College, University of South China, Hengyang, 421001, China.
Chuan WangInstitution of Pathogenic Biology, Medical College, University of South China, Hengyang, 421001, China.
Man XuInstitution of Pathogenic Biology, Medical College, University of South China, Hengyang, 421001, China.
Qian ChenInstitution of Pathogenic Biology, Medical College, University of South China, Hengyang, 421001, China.
Chunxue LuInstitution of Pathogenic Biology, Medical College, University of South China, Hengyang, 421001, China.
Yimou WuInstitution of Pathogenic Biology, Medical College, University of South China, Hengyang, 421001, China. yimouwu@sina.com.
University of South China · CNThe First Hospital of Changsha · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study evaluated the immune-protective efficacy of the Chlamydia psittaci (C. psittaci) plasmid protein CPSIT_p7 and analyzed the potential mechanisms of this protection. The current study used recombinant CPSIT_p7 protein with Freund's complete adjuvant and Freund's incomplete adjuvant to vaccinate BALB/c mice. Adjuvants alone or PBS formulated with the same adjuvants was used as negative controls. Mice were intranasally challenged with 10

Indexed as

AnimalsAntigens, BacterialBacterial LoadBacterial VaccinesCD4-Positive T-LymphocytesChlamydophila psittaciFemaleImmunity, CellularImmunizationInterferon-gammaLungMiceMice, Inbred BALB CPlasmidsPsittacosisVaccinationAntigens, BacterialBacterial VaccinesInterferon-gammaVaccines, SyntheticCD4+ T cellsCPSIT_p7C. psittaciPlasmid proteinProtective immunity

Identifiers

PMID30097797
OpenAlexW2886783264

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.