ArticleMikrochimica acta2018
An organic electrochemical transistor for determination of microRNA21 using gold nanoparticles and a capture DNA probe.
Article in Mikrochimica acta, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Isolation of Exosomes from MDA-MB-231 Cells Using a Paddle Screw System and Detection of TNBC-Associated Exosomal miRNAs.Micromachines · 2026Article
- CRISPR-Cas Systems Associated with Electrolyte-Gated Graphene-Based Transistors: How They Work and How to Combine Them.Biosensors · 2024Review
- Isolation and Characterization of Exosomes from Cancer Cells Using Antibody-Functionalized Paddle Screw-Type Devices and Detection of Exosomal miRNA Using Piezoelectric Biosensor.Sensors (Basel, Switzerland) · 2024Article
- Detection of Listeria monocytogenes in foods with a textile organic electrochemical transistor biosensor.Applied microbiology and biotechnology · 2023Article
- Micro- and nano-devices for electrochemical sensing.Mikrochimica acta · 2022Review
- Carbon nanodot-based electrogenerated chemiluminescence biosensor for miRNA-21 detection.Mikrochimica acta · 2021Article
- Combination of ultrathin micro-patterned MXene and PEDOT: Poly(styrenesulfonate) enables organic electrochemical transistor for amperometric determination of survivin protein in children osteosarcoma.Mikrochimica acta · 2021Article
- A sensitive and label-free electrochemical microRNA biosensor based on Polyamidoamine Dendrimer functionalized Polypyrrole nanowires hybrid.Mikrochimica acta · 2021Article
- Aluminosilicate Nanocomposite on Genosensor: A Prospective Voltammetry Platform for Epidermal Growth Factor Receptor Mutant Analysis in Non-small Cell Lung Cancer.Scientific reports · 2019Article
- AC Electrodeposition of PEDOT Films in Protic Ionic Liquids for Long-Term Stable Organic Electrochemical Transistors.Molecules (Basel, Switzerland) · 2019Article
- A review on nanomaterial-based field effect transistor technology for biomarker detection.Mikrochimica acta · 2019Review
- Biological Applications of Organic Electrochemical Transistors: Electrochemical Biosensors and Electrophysiology Recording.Frontiers in chemistry · 2019Review
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Authors and funding
7 authors.
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Abstract
A method is described for the determination of microRNA. It is based on the use of organic electrochemical transistors (OECTs) fabricated on a flexible poly(ethylene terephthalate) substrate. A gold electrode was modified with gold nanoparticles to immobilize the capture DNA probe and then served as the gate of the device. The detection of microRNA21 was realized by monitoring the change of the drain-source current after hybridization of capture DNA with microRNA21. Under optimal conditions, this biosensor exhibits good sensitivity and specificity. It works in the 5 pM to 20 nM microRNA concentration range and has a 2 pM detection limit. Graphical abstract Schematic of the organic electrochemical transistor-based microRNA21 biosensor. It constitutes a screen-printed carbon source (S) and drain (D) electrodes, a spin-coated poly(3,4-ethylenedioxythiophere):poly(styrene sulfonic acid) (PEDOT:PSS) film on the poly(ethylene terephthalate) (PET) substrate, and a gold gate modified with gold nanoparticles (Au NPs), capture probe, and 6-mercapto-1-hexanol (MCH).
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