ReviewNeuroradiology2018
Neuroimaging of central diabetes insipidus-when, how and findings.
Review in Neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Xanthomatous Hypophysitis: A Case Report and Comprehensive Literature Review.Frontiers in endocrinology · 2021Pooled it
- Pediatric endocrine disorders: a review of intracranial findings and appropriate imaging.Pediatric radiology · 2026Review
- Article
- Pituitary Stalk Lesion Sampling by Transsphenoidal Posterior Lobe Biopsy: A Case Series.Journal of neurological surgery. Part B, Skull base · 2026Article
- Arginine Vasopressin Deficiency and Oxytocin Deficiency in the Endocrine Clinic.The Journal of clinical endocrinology and metabolism · 2026Review
- Hypothalamic sarcoidosis in an older patient diagnosed by narrow band imaging-guided transcortical neuroendoscopic biopsy: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Analysis of factors associated with polyuria in spinal surgery: a retrospective study.BMC anesthesiology · 2025Article
- Hyperosmolar hyperglycemic state with severe hypernatremia coexisting with central diabetes insipidus: A case report and literature review.Open life sciences · 2025Article
- Deficiency of arginine vasopressin in children - diagnostic and therapeutic approaches to improve patients' quality of life based on a 25-year, single-centre retrospective analysis.Pediatric endocrinology, diabetes, and metabolism · 2024Article
- Panhypopituitarism Mimicking Acute Coronary Syndrome.Internal medicine (Tokyo, Japan) · 2023Article
- Endocrine side effects of immune checkpoint inhibitors.Frontiers in endocrinology · 2023Review
- Idiopathic partial central diabetes insipidus.Einstein (Sao Paulo, Brazil) · 2023Article
- Change in cephalocaudal tumor cavity diameter after transsphenoidal surgery is a predictor of diabetes insipidus in pituitary adenoma.European journal of medical research · 2022Article
- Central diabetes insipidus after total abdominal hysterectomy and bilateral salpingo-oophrectomy: A case report.Clinical case reports · 2022Article
- Masked diabetes insipidus in pituitary metastasis from breast cancer after thalamic biopsy: a case report.Journal of medical case reports · 2022Article
- Immune Checkpoint Inhibitor-Induced Central Diabetes Insipidus: Looking for the Needle in the Haystack or a Very Rare Side-Effect to Promptly Diagnose?Frontiers in oncology · 2022Review
- Late magnetic resonance imaging findings in trauma-induced central diabetes insipidus: Case report and review of literature.Radiology case reports · 2021Article
- Review
- Improvement in Pituitary Imaging After Targeted Therapy in Three Children withOncoTargets and therapy · 2020Article
- Lateral fluid-percussion injury leads to pituitary atrophy in rats.Scientific reports · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Central or neurogenic diabetes insipidus (CDI) is due to deficient synthesis or secretion of antidiuretic hormone (ADH), also known as arginine vasopressin peptide (AVP). It is clinically characterised by polydipsia and polyuria (urine output > 30 mL/kg/day) of dilute urine (< 250 mOsm/L). It is the result of a defect in one of more sites involving the hypothalamic osmoreceptors, supraoptic or paraventricular nuclei of the hypothalamus, median eminence of the hypothalamus, infundibulum or the posterior pituitary gland. A focused MRI pituitary gland or sella protocol is essential. There are several neuroimaging correlates and causes of CDI, illustrated in this review. The most common causes are benign or malignant neoplasms of the hypothalamic-pituitary axis (25%), surgery (20%), head trauma (16%) or familial causes (10%). No cause is identified in up to 30% of cases. Knowledge of the anatomy and physiology of the hypothalamo-neurohypophyseal axis is crucial when evaluating a patient with CDI. Establishing the aetiology of CDI with MRI in combination with clinical and biochemical assessment facilitates appropriate targeted treatment. The aim of the pictorial review is to illustrate the wide variety of causes of CDI on neuroimaging, highlight the optimal MRI protocol and to revise the detailed neuroanatomy and neurophysiology required to interpret these studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.