Evidence map›Paper›PMID 30097648›Full record

ArticleScientific reports2018

Adenosine Kinase couples sensing of cellular potassium depletion to purine metabolism.

Renata Rocha de Oliveira, Raphael Morales-Neto, Silvana Aparecida Rocco, Maurício Luis Sforça, Carla Cristina Polo, Celisa Caldana Costa Tonoli, Gustavo Fernando Mercaldi, Artur Torres Cordeiro, Mário Tyago Murakami, Kleber Gomes Franchini

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  5. Review
  6. S-Adenosyl-l-Methionine Salvage Impacts Psilocybin Formation in "Magic" Mushrooms.Chembiochem : a European journal of chemical biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Renata Rocha de OliveiraBrazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials, Campinas, São Paulo, 13083-970, Brazil.
Raphael Morales-NetoBrazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials, Campinas, São Paulo, 13083-970, Brazil.
Silvana Aparecida RoccoBrazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials, Campinas, São Paulo, 13083-970, Brazil.
Maurício Luis SforçaBrazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials, Campinas, São Paulo, 13083-970, Brazil.
Carla Cristina PoloBrazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials, Campinas, São Paulo, 13083-970, Brazil.
Celisa Caldana Costa TonoliBrazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials, Campinas, São Paulo, 13083-970, Brazil.
Gustavo Fernando MercaldiBrazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials, Campinas, São Paulo, 13083-970, Brazil.
Artur Torres CordeiroBrazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials, Campinas, São Paulo, 13083-970, Brazil.
Mário Tyago MurakamiBrazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials, Campinas, São Paulo, 13083-970, Brazil.
Kleber Gomes FranchiniBrazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials, Campinas, São Paulo, 13083-970, Brazil. kleber.franchini@lnbio.cnpem.br.
Brazilian Center for Research in Energy and Materials · BRBrazilian Biosciences National Laboratory · BRUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

Ministry of Science, Technology and Innovation | Conselho Nacional de Desenvolvimento Científico e Tecnológico (National Council for Scientific and Technological Development) 310536/2014-6Ministry of Science, Technology and Innovation | Conselho Nacional de Desenvolvimento Científico e Tecnológico (National Council for Scientific and Technological Development) 422790/2016-8
6 · The paper itself

Abstract

Adenosine Kinase (ADK) regulates the cellular levels of adenosine (ADO) by fine-tuning its metabolic clearance. The transfer of γ-phosphate from ATP to ADO by ADK involves regulation by the substrates and products, as well as by Mg

Indexed as

Metabolic Networks and PathwaysAdenosine KinaseAmino AcidsBinding SitesEnzyme ActivationKineticsMagnetic Resonance ImagingMolecular ConformationMutationPhosphorylationPotassiumProtein BindingPurinesStructure-Activity RelationshipAdenosine KinaseAmino AcidsPotassiumpurinePurines

Identifiers

PMID30097648
PMCPMC6086891
OpenAlexW2886696856

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.