Evidence map›Paper›PMID 30097582›Full record

ArticleNature communications2018

Biology and genome of a newly discovered sibling species of Caenorhabditis elegans.

Natsumi Kanzaki, Isheng J Tsai, Ryusei Tanaka, Vicky L Hunt, Dang Liu, Kenji Tsuyama, Yasunobu Maeda, Satoshi Namai, Ryohei Kumagai, Alan Tracey and 15 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 159 citations in OpenAlex.

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  20. Evolution of developmental bias explains divergent patterns of phenotypic evolution in two nematode clades.Proceedings of the National Academy of Sciences of the United States of America · 2025
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32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 8 institutions in 4 countries.

Natsumi KanzakiForestry and Forest Products Research Institute, Tsukuba, 305-8687, Japan.ORCID http://orcid.org/0000-0001-8752-1674
Isheng J TsaiBiodiversity Research Center, Academia Sinica, Taipei city, 11529, Taiwan.ORCID http://orcid.org/0000-0002-2123-5058
Ryusei TanakaFaculty of Medicine, University of Miyazaki, Miyazaki, 889-1692, Japan.
Vicky L HuntFaculty of Medicine, University of Miyazaki, Miyazaki, 889-1692, Japan.
Dang LiuBiodiversity Research Center, Academia Sinica, Taipei city, 11529, Taiwan.ORCID http://orcid.org/0000-0002-7805-889X
Kenji TsuyamaLaboratory of Developmental Dynamics, Graduate School of Life Sciences, Tohoku University, Sendai, 980-8577, Japan.ORCID http://orcid.org/0000-0003-4698-9961
Yasunobu MaedaFaculty of Medicine, University of Miyazaki, Miyazaki, 889-1692, Japan.
Satoshi NamaiLaboratory of Developmental Dynamics, Graduate School of Life Sciences, Tohoku University, Sendai, 980-8577, Japan.
Ryohei KumagaiLaboratory of Developmental Dynamics, Graduate School of Life Sciences, Tohoku University, Sendai, 980-8577, Japan.
Alan TraceyWellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, CB10 1SA, UK.
Nancy HolroydWellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, CB10 1SA, UK.
Stephen R DoyleWellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, CB10 1SA, UK.ORCID http://orcid.org/0000-0001-9167-7532
Gavin C WoodruffForestry and Forest Products Research Institute, Tsukuba, 305-8687, Japan.
Kazunori MuraseFaculty of Medicine, University of Miyazaki, Miyazaki, 889-1692, Japan.
Hiromi KitazumeFaculty of Medicine, University of Miyazaki, Miyazaki, 889-1692, Japan.
Cynthia ChaiHHMI and Division of Biology and Biological Engineering, Caltech, Pasadena, CA, 91125, USA.
Allison AkagiHHMI and Division of Biology and Biological Engineering, Caltech, Pasadena, CA, 91125, USA.
Oishika PandaBoyce Thompson Institute, and Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, 14853, USA.ORCID http://orcid.org/0000-0002-1217-8231
Huei-Mien KeBiodiversity Research Center, Academia Sinica, Taipei city, 11529, Taiwan.
Frank C SchroederBoyce Thompson Institute, and Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, 14853, USA.
John WangBiodiversity Research Center, Academia Sinica, Taipei city, 11529, Taiwan.
Matthew BerrimanWellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, CB10 1SA, UK.ORCID http://orcid.org/0000-0002-9581-0377
Paul W SternbergHHMI and Division of Biology and Biological Engineering, Caltech, Pasadena, CA, 91125, USA.ORCID http://orcid.org/0000-0002-7699-0173
Asako SugimotoLaboratory of Developmental Dynamics, Graduate School of Life Sciences, Tohoku University, Sendai, 980-8577, Japan. asugimoto@m.tohoku.ac.jp.ORCID http://orcid.org/0000-0001-6001-4293
Taisei KikuchiFaculty of Medicine, University of Miyazaki, Miyazaki, 889-1692, Japan. taisei_kikuchi@med.miyazaki-u.ac.jp.ORCID http://orcid.org/0000-0003-2759-9167
University of Miyazaki · JPBiodiversity Research Center, Academia Sinica · TWTohoku University · JPWellcome Sanger Institute · GBCalifornia Institute of Technology · USCornell University · USForestry and Forest Products Research Institute · JPUniversity of Oregon · US

Funding

Small Molecule Signaling in Caenorhabditis elegansR01GM088290 · NIGMS · BOYCE THOMPSON INST FOR PLANT RESEARCH · PI SCHROEDER, FRANK CLEMENS · 2010 to 2017
$2.2M
NIGMS NIH HHS R01 GM088290Wellcome Trust 206194
6 · The paper itself

Abstract

A 'sibling' species of the model organism Caenorhabditis elegans has long been sought for use in comparative analyses that would enable deep evolutionary interpretations of biological phenomena. Here, we describe the first sibling species of C. elegans, C. inopinata n. sp., isolated from fig syconia in Okinawa, Japan. We investigate the morphology, developmental processes and behaviour of C. inopinata, which differ significantly from those of C. elegans. The 123-Mb C. inopinata genome was sequenced and assembled into six nuclear chromosomes, allowing delineation of Caenorhabditis genome evolution and revealing unique characteristics, such as highly expanded transposable elements that might have contributed to the genome evolution of C. inopinata. In addition, C. inopinata exhibits massive gene losses in chemoreceptor gene families, which could be correlated with its limited habitat area. We have developed genetic and molecular techniques for C. inopinata; thus C. inopinata provides an exciting new platform for comparative evolutionary studies.

Indexed as

GenomeAmino Acid SequenceAnimalsBase SequenceCaenorhabditis elegansChemoreceptor CellsConserved SequenceDNA Transposable ElementsEvolution, MolecularFemaleGenetic VariationMaleMultigene FamilyRegulatory Sequences, Nucleic AcidRNA InterferenceSpecies SpecificityDNA Transposable Elements

Identifiers

PMID30097582
PMCPMC6086898
OpenAlexW2886996122

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.