Evidence map›Paper›PMID 30097528›Full record

ArticlePediatrics2018

Behavioral Health and Adult Milestones in Young Adults With Perinatal HIV Infection or Exposure.

Elaine J Abrams, Claude A Mellins, Amelia Bucek, Curtis Dolezal, Jeannette Raymond, Andrew Wiznia, Andrea Jurgrau, Mahrukh Bamji, Cheng-Shiun Leu, Yiu Kee Warren Ng

Abstract read
In one paragraph

Article in Pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Aging of adult lifetime survivors with perinatal HIV.Current opinion in HIV and AIDS · 2025
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Elaine J AbramsICAP at Columbia University, Mailman School of Public Health, eja1@cumc.columbia.edu.
Claude A MellinsHIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute, Columbia University, New York, New York.
Amelia BucekHIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute, Columbia University, New York, New York.
Curtis DolezalHIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute, Columbia University, New York, New York.
Jeannette RaymondHIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute, Columbia University, New York, New York.
Andrew WizniaJacobi Medical Center, Albert Einstein College of Medicine, Bronx, New York.
Andrea JurgrauNew York-Presbyterian Hospital/Columbia University Medical Center, New York, New York; and.
Mahrukh BamjiMetropolitan Hospital Center, New York, New York.
Cheng-Shiun LeuHIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute, Columbia University, New York, New York.
Yiu Kee Warren NgNew York-Presbyterian Hospital/Columbia University Medical Center, New York, New York; and.

Funding

The Statistics, Data Science, and Data Management (SDM) CoreP30MH043520 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI Claude Ann Mellins · 2003 to 2026
$48.2M
Transitioning from childhood to adulthood: the impact of perinatal HIV infectionR01MH069133 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MELLINS, CLAUDE ANN · 2004 to 2023
$14.3M
NIMH NIH HHS P30 MH043520NIMH NIH HHS R01 MH069133
6 · The paper itself

Abstract

backgroundYoung adults living with perinatally acquired HIV infection (PHIVYAs) are at risk for poor biomedical and behavioral health outcomes. Few studies offer a comprehensive overview of the functioning of this population in young adulthood and the role of HIV.

methodsData come from the Child and Adolescent Self-Awareness and Health Study, a longitudinal behavioral health cohort study of PHIVYAs and perinatally HIV-exposed but uninfected young adults (PHEUYAs) who are compared on psychiatric and neurocognitive functioning, sexual and substance use behaviors, health and reproductive outcomes, and young adult milestones.

resultsOverall, 27% of participants met criteria for a psychiatric disorder, including mood (11%), anxiety (22%), and substance use (28%), with no HIV status differences. PHIVYAs performed worse on 2 neurocognitive tests. There were no HIV status differences in condomless sex (41%) or pregnancies (41% women; 38% men). Both groups exhibited similar adult milestones: 67% graduated high school or an equivalent, 19% were in college, and 42% were employed. However, 38% were neither in school or working, 12% reported incarceration, and 16% were ever homeless. Among PHIVYAs, 36% were viremic (>200 copies per mL), and 15% were severely immunocompromised (CD4

conclusionsMany PHIVYAs achieve adult milestones related to school, employment, sexual relationships, and starting families. However, they and PHEUYAs have high rates of psychiatric and substance use disorders and behavioral risks, which can jeopardize long-term health and adult functioning, particularly in the context of HIV. These findings underscore an urgent need to escalate interventions.

Indexed as

AdolescentAdolescent BehaviorAdultChildCohort StudiesFemaleHIV InfectionsHumansInfectious Disease Transmission, VerticalLongitudinal StudiesMaleMental DisordersNew YorkPregnancySexual BehaviorYoung Adult

Identifiers

PMID30097528
PMCPMC6317560

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.