Evidence map›Paper›PMID 30097505›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2018

Evaluation of

Hiroto Kuwabara, Robert A Comley, Edilio Borroni, Michael Honer, Kelly Kitmiller, Joshua Roberts, Lorena Gapasin, Anil Mathur, Gregory Klein, Dean F Wong

Abstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Evaluation of tau deposition usingAlzheimer's research & therapy · 2022
    Trial
  2. Evaluation of [Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Trial
  3. In-depth multimodal validation ofExperimental & molecular medicine · 2026
    Article
  4. Longitudinal monitoring of tau aggregation in progressive supranuclear palsy with [Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  5. Article
  6. Exploring the origins of frequent tau-PET signal in vermal and adjacent regions.European journal of nuclear medicine and molecular imaging · 2025
    Article
  7. Radiosynthesis,ACS chemical neuroscience · 2025
    Article
  8. Review
  9. In Vivo Head-to-Head Comparison of [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  10. Review
  11. Test-retest performance of [Imaging neuroscience (Cambridge, Mass.) · 2024
    Article
  12. Article
  13. The Use of Tau PET to Stage Alzheimer Disease According to the Braak Staging Framework.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Review
  14. Review
  15. Observational
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hiroto KuwabaraDepartment of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland hkuwaba1@jhmi.edu edilio.borroni@roche.com.
Robert A ComleyPharma Research and Early Development, Hoffmann-La Roche, Basel, Switzerland.
Edilio BorroniPharma Research and Early Development, Hoffmann-La Roche, Basel, Switzerland hkuwaba1@jhmi.edu edilio.borroni@roche.com.
Michael HonerPharma Research and Early Development, Hoffmann-La Roche, Basel, Switzerland.
Kelly KitmillerDepartment of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Joshua RobertsDepartment of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Lorena GapasinDepartment of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Anil MathurDepartment of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Gregory KleinPharma Research and Early Development, Hoffmann-La Roche, Basel, Switzerland.
Dean F WongDepartment of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Funding

IMAGING RESEARCH IN NEUROPSYCHIATRY AND DRUG ABUSEK24DA000412 · NIDA · JOHNS HOPKINS UNIVERSITY · PI WONG, DEAN FOSTER · 2000 to 2009
$1.5M
NIDA NIH HHS K24 DA000412
6 · The paper itself

Abstract

The availability of tau PET radioligands enables quantitative assessment of tau density and distribution in the human brain. We evaluated the kinetics of a novel radioligand,

Indexed as

RadiopharmaceuticalsAdultAgedAlzheimer DiseaseBrainCase-Control StudiesFemaleFluorine RadioisotopesFunctional NeuroimagingHumansMagnetic Resonance ImagingMaleMiddle AgedModels, NeurologicalPositron-Emission TomographyRadioligand AssayFluorine-18Fluorine RadioisotopesMAPT protein, humanRadiopharmaceuticalstau Proteins18F-RO6958948 for tau imagingAlzheimer diseaseneurologyPETradiotracer tissue kinetics

Identifiers

PMID30097505
PMCPMC6278898

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.