Evidence map›Paper›PMID 30097490›Full record

ArticleBMJ quality & safety2019

Value of hospital resources for effective pressure injury prevention: a cost-effectiveness analysis.

William V Padula, Peter J Pronovost, Mary Beth F Makic, Heidi L Wald, Dane Moran, Manish K Mishra, David O Meltzer

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in BMJ quality & safety, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04649853 (Wound Care and Pressure Injury Through the Continuum of Care), which is not on this map. Cited by 46 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 5 pooled it
46.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04649853 unknown statusnot on this mapstarted 2020, after this paper: background citation

Wound Care and Pressure Injury Through the Continuum of Care

TypeobservationalSponsorRegional Medical Center of San JoseRan2020 to 2021Enrolled352ConditionsWound, Pressure InjuryArmsStandardized nursing care
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 5 syntheses or guidelines pooled it, 173 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Consolidated Health Economic Evaluation Reporting Standards for Interventions That Use Artificial Intelligence (CHEERS-AI).Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

William V PadulaHealth Policy & Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Peter J PronovostArmstrong Institute for Patient Safety and Quality, Johns Hopkins Medicine, Baltimore, Maryland, USA.
Mary Beth F MakicCollege of Nursing, University of Colorado, Aurora, Colorado, USA.
Heidi L WaldMedicine, University of Colorado Denver School of Medicine, Aurora, Colorado, USA.
Dane MoranEmergency Medicine, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0002-0383-4305
Manish K MishraCommunity and Family Medicine, Dartmouth College Geisel School of Medicine, Hanover, New Hampshire, USA.
David O MeltzerDepartment of Medicine, Center for Health and the Social Sciences, University of Chicago, Chicago, Illinois, USA.
Johns Hopkins University · USBaylor College of Medicine · USDartmouth College · USUniversity of Chicago · USUniversity of Colorado Denver · USUniversity of Colorado System · US

Funding

Using EHR Data to Dynamically Target Patients for Braden Scale Risk-AssessmentF32HS023710 · AHRQ · UNIVERSITY OF CHICAGO · PI PADULA, WILLIAM VINCENT · 2014 to 2014
$68k
AHRQ HHS F32 HS023710
6 · The paper itself

Abstract

objectiveHospital-acquired pressure injuries are localised skin injuries that cause significant mortality and are costly. Nursing best practices prevent pressure injuries, including time-consuming, complex tasks that lack payment incentives. The Braden Scale is an evidence-based stratification tool nurses use daily to assess pressure-injury risk. Our objective was to analyse the cost-utility of performing repeated risk-assessment for pressure-injury prevention in all patients or high-risk groups.

designCost-utility analysis using Markov modelling from US societal and healthcare sector perspectives within a 1-year time horizon.

settingPatient-level longitudinal data on 34 787 encounters from an academic hospital electronic health record (EHR) between 2011 and 2014, including daily Braden scores. Supervised machine learning simulated age-adjusted transition probabilities between risk levels and pressure injuries.

participantsHospitalised adults with Braden scores classified into five risk levels: very high risk (6-9), high risk (10-11), moderate risk (12-14), at-risk (15-18), minimal risk (19-23).

interventionsStandard care, repeated risk assessment in all risk levels or only repeated risk assessment in high-risk strata based on machine-learning simulations.

main outcome measuresCosts (2016 $US) of pressure-injury treatment and prevention, and quality-adjusted life years (QALYs) related to pressure injuries were weighted by transition probabilities to calculate the incremental cost-effectiveness ratio (ICER) at $100 000/QALY willingness-to-pay. Univariate and probabilistic sensitivity analyses tested model uncertainty.

resultsSimulating prevention for all patients yielded greater QALYs at higher cost from societal and healthcare sector perspectives, equating to ICERs of $2000/QALY and $2142/QALY, respectively. Risk-stratified follow-up in patients with Braden scores <15 dominated standard care. Prevention for all patients was cost-effective in >99% of probabilistic simulations.

conclusionOur analysis using EHR data maintains that pressure-injury prevention for all inpatients is cost-effective. Hospitals should invest in nursing compliance with international prevention guidelines.

Indexed as

Cost-Benefit AnalysisCost of IllnessEconomics, HospitalGuideline AdherenceHospital CostsHospitalsHumansLongitudinal StudiesMachine LearningMarkov ChainsModels, EconomicPractice Guidelines as TopicPressure UlcerQuality-Adjusted Life YearsRisk AssessmentUnited Statescost-effectivenesshealth services researchnurses

Identifiers

PMID30097490
PMCPMC6365919
OpenAlexW2885613452

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.