Evidence map›Paper›PMID 30097106›Full record

ArticleMethods in enzymology2018

QueE: A Radical SAM Enzyme Involved in the Biosynthesis of 7-Deazapurine Containing Natural Products.

Julia K Lewis, Nathan A Bruender, Vahe Bandarian

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Methods in enzymology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Julia K LewisDepartment of Chemistry, University of Utah, Salt Lake City, UT, United States.
Nathan A BruenderDepartment of Chemistry and Biochemistry, St. Cloud State University, St. Cloud, MN, United States.
Vahe BandarianDepartment of Chemistry, University of Utah, Salt Lake City, UT, United States. Electronic address: vahe@chem.utah.edu.
University of Utah · USSt. Cloud State University · US

Funding

This proposal is in response to PA-20-272. It is an administrative supplement to purchase a new peptide synthesizer to support R35 GM126956R35GM126956 · NIGMS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI VAHE BANDARIAN · 2018 to 2026
$5.3M
Biosynthesis of Deazapurine-Containing MetabolitesR01GM072623 · NIGMS · UNIVERSITY OF UTAH · PI BANDARIAN, VAHE · 2005 to 2017
$3.9M
Mechanistic studies of thioether crosslink formation in peptidesR01GM120638 · NIGMS · UNIVERSITY OF UTAH · PI BANDARIAN, VAHE · 2016 to 2017
$695k
NIGMS NIH HHS R01 GM072623NIGMS NIH HHS R01 GM120638NIGMS NIH HHS R35 GM126956
6 · The paper itself

Abstract

7-Carboxy-7-deazaguanine (CDG) is a common intermediate in the biosynthesis of 7-deazapurine-containing natural products. The biosynthesis of CDG from GTP requires three enzymes: GTP cyclohydrolase I, 6-carboxy-5,6,7,8-tetrahydropterin (CPH

Indexed as

Bacillus subtilisBacterial ProteinsBiocatalysisBiological ProductsCarbon-Nitrogen LyasesFree RadicalsPurinesRecombinant ProteinsS-Adenosylmethionine7-deazapurineBacterial ProteinsBiological ProductsCarbon-Nitrogen LyasesFree RadicalsPurinesRecombinant ProteinsS-Adenosylmethionine7-DeazapurineCDG synthaseRadical SAMtRNA modification

Identifiers

PMID30097106
PMCPMC6484087
OpenAlexW2884485338

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.