Evidence map›Paper›PMID 30096951›Full record

ArticleNutrients2018

Adipocytokine Regulation and Antiangiogenic Activity Underlie the Molecular Mechanisms of Therapeutic Effects of Phyllanthus niruri against Non-Alcoholic Fatty Liver Disease.

Raghdaa Hamdan Al Zarzour, Mohammed A Alshawsh, Muhammad Asif, Majed Ahmed Al-Mansoub, Zahurin Mohamed, Mariam Ahmad, Amin Malik Shah Abdul Majid, Mohd Zaini Asmawi, Gurjeet Kaur, Dhamraa Waleed Al-Dualimi and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. International journal of molecular sciences · 2023
    Article
  6. Pharmaceuticals (Basel, Switzerland) · 2023
    Article
  7. Article
  8. Review
  9. Frontiers in cardiovascular medicine · 2022
    Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Raghdaa Hamdan Al ZarzourDiscipline of Pharmacology, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden 11800, Penang, Malaysia. raghdaa.alzarzour@yahoo.com.ORCID 0000-0002-9794-3552
Mohammed A AlshawshDepartment of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia. alshweshmam@um.edu.my.
Muhammad AsifDiscipline of Pharmacology, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden 11800, Penang, Malaysia. asif_pharmacist45@yahoo.com.
Majed Ahmed Al-MansoubDiscipline of Pharmacology, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden 11800, Penang, Malaysia. majed@usm.my.ORCID 0000-0003-0162-5830
Zahurin MohamedDepartment of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia. zahurin@um.edu.my.
Mariam AhmadDiscipline of Pharmacology, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden 11800, Penang, Malaysia. mariam@usm.my.
Amin Malik Shah Abdul MajidDiscipline of Pharmacology, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden 11800, Penang, Malaysia. aminmalikshah@usm.my.
Mohd Zaini AsmawiDiscipline of Pharmacology, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden 11800, Penang, Malaysia. amzaini@usm.my.ORCID 0000-0003-0420-6797
Gurjeet KaurInstitute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Minden 11800, Penang, Malaysia. gurjeet@usm.my.
Dhamraa Waleed Al-DualimiDiscipline of Pharmacology, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden 11800, Penang, Malaysia. dhamora@yahoo.com.
Mun Fei YamDiscipline of Pharmacology, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden 11800, Penang, Malaysia. yammunfei@yahoo.com.
Universiti Sains Malaysia · MYUniversity of Malaya · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The growth of adipose tissues is considered angiogenesis-dependent during non-alcoholic fatty liver disease (NAFLD). We have recently reported that our standardized 50% methanolic extract (ME) of

Indexed as

PhyllanthusAdipokinesAngiogenesis InhibitorsAngiogenic ProteinsAnimalsCell LineDisease Models, AnimalGene Expression RegulationHumansLiverMaleNeovascularization, PhysiologicNon-alcoholic Fatty Liver DiseasePlant ExtractsRats, Sprague-DawleySignal TransductionAdipokinesAngiogenesis InhibitorsAngiogenic ProteinsPlant Extractsadipocytokinesadipose tissuesantiangiogenic effectgene expressionnon-alcoholic fatty liver disease (NAFLD)Phyllanthus niruri

Identifiers

PMID30096951
PMCPMC6115813
OpenAlexW2886633577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.