Evidence map›Paper›PMID 30096904›Full record

ReviewToxins2018

Human Poisoning from Marine Toxins: Unknowns for Optimal Consumer Protection.

Natalia Vilariño, M Carmen Louzao, Paula Abal, Eva Cagide, Cristina Carrera, Mercedes R Vieytes, Luis M Botana

Abstract readReview
In one paragraph

Review in Toxins, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
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  6. Article
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  8. Review
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  10. Article
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  13. Total cucurbitacins fromFrontiers in pharmacology · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Insights into ToxicToxins · 2023
    Review
  18. Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Natalia VilariñoDepartamento de Farmacología, Facultad de Veterinaria, Universidade de Santiago de Compostela, 27002 Lugo, Spain. natalia.vilarino@usc.es.
M Carmen LouzaoDepartamento de Farmacología, Facultad de Veterinaria, Universidade de Santiago de Compostela, 27002 Lugo, Spain. mcarmen.louzao@usc.es.ORCID 0000-0002-3072-0637
Paula AbalDepartamento de Farmacología, Facultad de Veterinaria, Universidade de Santiago de Compostela, 27002 Lugo, Spain. paula.abal@usc.es.ORCID 0000-0003-2962-4389
Eva CagideLaboratorio CIFGA S.A., Plaza Santo Domingo 20-5°, 27001 Lugo, Spain. evacagide@cifga.es.ORCID 0000-0002-1965-9601
Cristina CarreraDepartamento de Farmacología, Facultad de Veterinaria, Universidade de Santiago de Compostela, 27002 Lugo, Spain. cristina.carrera@usc.es.
Mercedes R VieytesDepartamento de Fisiología, Facultad de Veterinaria, Universidade de Santiago de Compostela, 27002 Lugo, Spain. mmercedes.rodriguez@usc.es.
Luis M BotanaDepartamento de Farmacología, Facultad de Veterinaria, Universidade de Santiago de Compostela, 27002 Lugo, Spain. luis.botana@usc.es.ORCID 0000-0003-2153-6608

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marine biotoxins are produced by aquatic microorganisms and accumulate in shellfish or finfish following the food web. These toxins usually reach human consumers by ingestion of contaminated seafood, although other exposure routes like inhalation or contact have also been reported and may cause serious illness. This review shows the current data regarding the symptoms of acute intoxication for several toxin classes, including paralytic toxins, amnesic toxins, ciguatoxins, brevetoxins, tetrodotoxins, diarrheic toxins, azaspiracids and palytoxins. The information available about chronic toxicity and relative potency of different analogs within a toxin class are also reported. The gaps of toxicological knowledge that should be studied to improve human health protection are discussed. In general, gathering of epidemiological data in humans, chronic toxicity studies and exploring relative potency by oral administration are critical to minimize human health risks related to these toxin classes in the near future.

Indexed as

Shellfish PoisoningAcrylamidesAnimalsHumansMarine ToxinsOkadaic AcidSpiro CompoundsAcrylamidesMarine ToxinsOkadaic AcidSpiro Compoundsacute toxicitybiotoxinchronic toxicityintoxicationtoxicity equivalency factor

Identifiers

PMID30096904
PMCPMC6116008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.