Evidence map›Paper›PMID 30096857›Full record

ArticleNanomaterials (Basel, Switzerland)2018

Hexagonal Boron Nitride Functionalized with Au Nanoparticles-Properties and Potential Biological Applications.

Magdalena Jedrzejczak-Silicka, Martyna Trukawka, Mateusz Dudziak, Katarzyna Piotrowska, Ewa Mijowska

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 83 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Molecular-Level Interactions between Engineered Materials and Cells.International journal of molecular sciences · 2019
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Magdalena Jedrzejczak-SilickaLaboratory of Cytogenetics, West Pomeranian University of Technology, Szczecin, Klemensa Janickiego 29, 71-270 Szczecin, Poland. mjedrzejczak@zut.edu.pl.ORCID 0000-0003-4818-6265
Martyna TrukawkaNanomaterials Physicochemistry Department, West Pomeranian University of Technology, Szczecin, Piastow Avenue 45, 70-311 Szczecin, Poland. martyna.brylak@zut.edu.pl.
Mateusz DudziakNanomaterials Physicochemistry Department, West Pomeranian University of Technology, Szczecin, Piastow Avenue 45, 70-311 Szczecin, Poland. mateusz.dudziak@zut.edu.pl.ORCID 0000-0002-5803-8525
Katarzyna PiotrowskaDepartment of Physiology, Pomeranian Medical University in Szczecin, Powstancow Wlkp. 72, 70-111 Szczecin, Poland. piot.kata@gmail.com.
Ewa MijowskaNanomaterials Physicochemistry Department, West Pomeranian University of Technology, Szczecin, Piastow Avenue 45, 70-311 Szczecin, Poland. emijowska@zut.edu.pl.
West Pomeranian University of Technology in Szczecin · PLPomeranian Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hexagonal boron nitride is often referred to as white graphene. This is a 2D layered material, with a structure similar to graphene. It has gained many applications in cosmetics, dental cements, ceramics etc. Hexagonal boron nitride is also used in medicine, as a drug carrier similar as graphene or graphene oxide. Here we report that this material can be exfoliated in two steps: chemical treatment (via modified Hummers method) followed by the sonication treatment. Afterwards, the surface of the obtained material can be efficiently functionalized with gold nanoparticles. The mitochondrial activity was not affected in L929 and MCF-7 cell line cultures during 24-h incubation, whereas longer incubation (for 48, and 72 h) with this nanocomposite affected the cellular metabolism. Lysosome functionality, analyzed using the NR uptake assay, was also reduced in both cell lines. Interestingly, the rate of MCF-7 cell proliferation was reduced when exposed to h-BN loaded with gold nanoparticles. It is believed that h-BN nanocomposite with gold nanoparticles is an attractive material for cancer drug delivery and photodynamic therapy in cancer killing.

Indexed as

boron nitridecytobiocompatibilityfunctionalizationgold nanoparticlesnanocomposite

Identifiers

PMID30096857
PMCPMC6116289
OpenAlexW2886095571

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.