Evidence map›Paper›PMID 30096805›Full record

ArticleNutrients2018

Pectolinarigenin Induced Cell Cycle Arrest, Autophagy, and Apoptosis in Gastric Cancer Cell via PI3K/AKT/mTOR Signaling Pathway.

Ho Jeong Lee, Venu Venkatarame Gowda Saralamma, Seong Min Kim, Sang Eun Ha, Suchismita Raha, Won Sup Lee, Eun Hee Kim, Sang Joon Lee, Jeong Doo Heo, Gon Sup Kim

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 1 pooled it
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 1 synthesis or guideline pooled it, 132 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Pectolinarigenin fromPharmaceuticals (Basel, Switzerland) · 2026
    Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Anticancer Potential of Bioactive Compounds inCancer management and research · 2025
    Review
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  17. Review
  18. [Kuwanon G inhibits growth, migration and invasion of gastric cancer cells by regulating the PI3K/AKT/mTOR pathway].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024
    Article
  19. Article
  20. Article

21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Ho Jeong LeeResearch Institute of Life science and College of Veterinary Medicine, Gyeongsang National University, 501 Jinju-daero, Jinju 52828, Korea. lhj1990y@gmail.com.
Venu Venkatarame Gowda SaralammaResearch Institute of Life science and College of Veterinary Medicine, Gyeongsang National University, 501 Jinju-daero, Jinju 52828, Korea. gowdavenu27@gmail.com.
Seong Min KimResearch Institute of Life science and College of Veterinary Medicine, Gyeongsang National University, 501 Jinju-daero, Jinju 52828, Korea. ksm4234@naver.com.ORCID 0000-0003-3359-7504
Sang Eun HaResearch Institute of Life science and College of Veterinary Medicine, Gyeongsang National University, 501 Jinju-daero, Jinju 52828, Korea. sangdis2@naver.com.
Suchismita RahaDepartment of Internal Medicine, Gyeongsang National University Cancer Center, School of Medicine, Gyeongsang National University, 15 Jinju-daero, Jinju 52727, Korea. suchibiodash@gmail.com.
Won Sup LeeDepartment of Internal Medicine, Gyeongsang National University Cancer Center, School of Medicine, Gyeongsang National University, 15 Jinju-daero, Jinju 52727, Korea. lwshmo@gnu.ac.kr.
Eun Hee KimDepartment of Nursing Science, International University of Korea, 965 Dongbu-ro, Jinju 52833, Korea. iuknurse@nate.com.
Sang Joon LeeGyeongnam Department of Environment Toxicology and Chemistry, Biological Resources Research Group, Korea Institute of Toxicology, 17 Jegok-gil, Jinju 52834, Korea. sjlee@kitox.re.kr.
Jeong Doo HeoGyeongnam Department of Environment Toxicology and Chemistry, Biological Resources Research Group, Korea Institute of Toxicology, 17 Jegok-gil, Jinju 52834, Korea. jdher@kitox.re.kr.
Gon Sup KimResearch Institute of Life science and College of Veterinary Medicine, Gyeongsang National University, 501 Jinju-daero, Jinju 52828, Korea. gonskim@gnu.ac.kr.ORCID 0000-0002-0844-1009
Gyeongsang National University · KRKorea Institute of Toxicology · KRInternational University of Korea · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pectolinarigenin (PEC), a natural flavonoid present in

Indexed as

Antineoplastic Agents, PhytogenicApoptosisApoptosis Regulatory ProteinsAutophagyAutophagy-Related ProteinsCell Cycle CheckpointsCell Line, TumorChromonesHumansPhosphatidylinositol 3-KinaseProto-Oncogene Proteins c-aktSignal TransductionStomach NeoplasmsTOR Serine-Threonine KinasesAntineoplastic Agents, PhytogenicApoptosis Regulatory ProteinsAutophagy-Related ProteinsChromonesMTOR protein, humanpectolinarigeninPhosphatidylinositol 3-KinaseProto-Oncogene Proteins c-aktTOR Serine-Threonine Kinasesapoptosisautophagygastric cancerpectolinarigeninPI3K/AKT/mTOR

Identifiers

PMID30096805
PMCPMC6115855
OpenAlexW2886108415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.