Evidence map›Paper›PMID 30096581›Full record

ArticleEnvironmental toxicology and pharmacology2018

Altered formation of the iron oxide nanoparticle-biocorona due to individual variability and exercise.

Lisa M Kobos, Sherleen Xue-Fu Adamson, Sheelagh Evans, Timothy P Gavin, Jonathan H Shannahan

Abstract read
In one paragraph

Article in Environmental toxicology and pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Inhalation toxicology · 2019
    Article
  8. Pulmonary iron oxide (FeHuman & experimental toxicology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lisa M KobosSchool of Health Sciences, College of Human and Health Sciences, Purdue University, West Lafayette, IN, 47907, USA.
Sherleen Xue-Fu AdamsonSchool of Health Sciences, College of Human and Health Sciences, Purdue University, West Lafayette, IN, 47907, USA.
Sheelagh EvansHealth and Kinesiology, College of Human and Health Sciences, Purdue University, West Lafayette, IN, 47907, USA.
Timothy P GavinHealth and Kinesiology, College of Human and Health Sciences, Purdue University, West Lafayette, IN, 47907, USA.
Jonathan H ShannahanSchool of Health Sciences, College of Human and Health Sciences, Purdue University, West Lafayette, IN, 47907, USA. Electronic address: jshannah@purdue.edu.

Funding

Disease-Induced Modification in Nanoparticle-Corona Identity and ToxicityR00ES024392 · NIEHS · PURDUE UNIVERSITY · PI SHANNAHAN, JONATHAN HENRY · 2017 to 2019
$747k
Disease-Induced Modification in Nanoparticle-Corona Identity and ToxicityK99ES024392 · NIEHS · UNIVERSITY OF COLORADO DENVER · PI SHANNAHAN, JONATHAN HENRY · 2015 to 2016
$180k
NIEHS NIH HHS K99 ES024392NIEHS NIH HHS R00 ES024392
6 · The paper itself

Abstract

Nanoparticles (NPs), introduced into a biological environment, accumulate a coating of biomolecules or biocorona (BC). Although the BC has toxicological and pharmacological consequences, the effects of inter-individual variability and exercise on NP-BC formation are unknown. We hypothesized that NPs incubated in plasma form distinct BCs between individuals, and exercise causes additional intra-individual alterations. 20 nm iron oxide (Fe

Indexed as

ExerciseAdultBiological Variation, PopulationBlood GlucoseFemaleHumansInsulinLipidsMagnetite NanoparticlesMaleProtein CoronaProteomicsU937 CellsYoung AdultBlood GlucoseInsulinLipidsMagnetite NanoparticlesProtein CoronaCholesterolExerciseMacrophagesNanotoxicologyProteomicsTriglycerides

Identifiers

PMID30096581
PMCPMC6112769

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.