ArticleHuman brain mapping2018
Reduced local segregation of single-subject gray matter networks in adult PTSD.
Article in Human brain mapping, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Associations between resting-state functional connectivity and treatment response in a randomized clinical trial for posttraumatic stress disorder.Depression and anxiety · 2020Trial
- Resolving Heterogeneity in Posttraumatic Stress Disorder Using Individualized Structural Covariance Network Analysis.Depression and anxiety · 2024Article
- Causal effects of nonalcoholic fatty liver disease on cerebral cortical structure: a Mendelian randomization analysis.Frontiers in endocrinology · 2023Article
- Altered single-subject gray matter structural networks in drug-naïve attention deficit hyperactivity disorder children.Human brain mapping · 2022Article
- Altered Structural Brain Network Topology in Patients With Primary Craniocervical Dystonia.Frontiers in neurology · 2022Article
- Disrupted brain gray matter networks in drug-naïve participants with essential tremor.Neuroradiology · 2021Article
- Individualized Prediction of PTSD Symptom Severity in Trauma Survivors From Whole-Brain Resting-State Functional Connectivity.Frontiers in behavioral neuroscience · 2020Article
- Aberrant Gray Matter Networks in Non-comorbid Medication-Naive Patients With Major Depressive Disorder and Those With Social Anxiety Disorder.Frontiers in human neuroscience · 2020Article
- Topological Regularization of Networks in Adult Patients with Moderate-to-Severe Obstructive Sleep Apnea-Hypopnea Syndrome: A Structural MRI Study.Nature and science of sleep · 2020Article
- Large-scale white matter network reorganization in posttraumatic stress disorder.Human brain mapping · 2019Article
- Reduced local segregation of single-subject gray matter networks in adult PTSD.Human brain mapping · 2018Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To psychoradiologically investigate the topological organization of single-subject gray matter networks in patients with PTSD. Eighty-nine adult PTSD patients and 88 trauma-exposed controls (TEC) underwent a structural T1 magnetic resonance imaging scan. The single-subject brain structural networks were constructed based on gray matter similarity of 90 brain regions. The area under the curve (AUC) of each network metric was calculated and both global and nodal network properties were measured in graph theory analysis. We used nonparametric permutation tests to identify group differences in topological metrics. Relationships between brain network measures and clinical symptom severity were analyzed in the PTSD group. Compared with TEC, brain networks of PTSD patients were characterized by decreased clustering coefficient (C
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.