ArticleAmerican journal of respiratory cell and molecular biology2018
Alveolar Micromechanics in Bleomycin-induced Lung Injury.
Article in American journal of respiratory cell and molecular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
48 citing papers in PubMed, 66 citations in OpenAlex.
- Tracking respiratory mechanics around natural breathing rates via variable ventilation.Scientific reports · 2020Trial
- Extracellular matrix remodeling modifies structural responses to ventilator-induced lung injury: a multiscale correlative imaging study.Respiratory research · 2026Article
- Low PEEP ventilation in TGF-β1 induced lung injury triggers a reversible lung mechanical deterioration without promoting persistent structural damage.Scientific reports · 2026Article
- TLR9-mediated innate immune signaling contributes to acetaminophen-induced injury in the developing lung.American journal of physiology. Lung cellular and molecular physiology · 2026Article
- Alveolar Type 2 Cell Dysfunction Is Associated with Bile Acid Alterations in Experimental Hepatopulmonary Syndrome.American journal of respiratory cell and molecular biology · 2026Article
- Peroxiredoxin 1 mediates bleomycin-induced acute lung injury in mice via macrophage NOD1/NF-κB axis.Respiratory research · 2026Article
- Artificial intelligence-assisted multiscale lung modeling to predict alveolar septal wall stress.Acta biomaterialia · 2026Article
- Computer model-based injury prediction and evaluation of lung function in mice with acute and ventilator-induced lung injuries.American journal of physiology. Lung cellular and molecular physiology · 2025Article
- Nanoscale structural alteration of lung collagen in response to strain and bleomycin injury.Scientific reports · 2025Article
- Article
- Cyclic mechanical loading of photopolymerized methacrylated hydrogels for probing interdependent effects of strain, stiffness, and substrate composition in pulmonary fibrogenesis.Scientific reports · 2025Article
- Dynamic driving pressure predicts ventilator-induced lung injury in mice with and without endotoxin-induced acute lung injury.American journal of physiology. Lung cellular and molecular physiology · 2025Article
- The fix is not yet in: recommendation for fixation of lungs within physiological/pathophysiological volume range in preclinical pulmonary structure-function studies.American journal of physiology. Lung cellular and molecular physiology · 2024Review
- Exploring alveolar recruitability using positive end-expiratory pressure in mice overexpressing TGF-β1: a structure-function analysis.Scientific reports · 2024Article
- Antenatal Endotoxin Induces Dysanapsis in Experimental Bronchopulmonary Dysplasia.American journal of respiratory cell and molecular biology · 2024Article
- Emerging delivery approaches for targeted pulmonary fibrosis treatment.Advanced drug delivery reviews · 2024Review
- CNP-miR146a improves outcomes in a two-hit acute- and ventilator-induced lung injury model.Nanomedicine : nanotechnology, biology, and medicine · 2023Article
- Potential protective effect of 3,3'-methylenebis(1-ethyl-4-hydroxyquinolin-2(1H)-one) against bleomycin-induced lung injury in male albino rat via modulation of Nrf2 pathway: biochemical, histological, and immunohistochemical study.Naunyn-Schmiedeberg's archives of pharmacology · 2023Article
- Differential effects of two-hit models of acute and ventilator-induced lung injury on lung structure, function, and inflammation.Frontiers in physiology · 2023Article
- Acinar micromechanics in health and lung injury: what we have learned from quantitative morphology.Frontiers in physiology · 2023Review
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
Abstract
Lung injury results in intratidal alveolar recruitment and derecruitment and alveolar collapse, creating stress concentrators that increase strain and aggravate injury. In this work, we sought to describe alveolar micromechanics during mechanical ventilation in bleomycin-induced lung injury and surfactant replacement therapy. Structure and function were assessed in rats 1 day and 3 days after intratracheal bleomycin instillation and after surfactant replacement therapy. Pulmonary system mechanics were measured during ventilation with positive end-expiratory pressures (PEEPs) between 1 and 10 cm H
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.