Trial reportObstetrics and gynecology2018
Paracervical Block for Intrauterine Device Placement Among Nulliparous Women: A Randomized Controlled Trial.
Trial report in Obstetrics and gynecology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 9 registered trials, which are not on this map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pain Control for Intrauterine Device Placement: A Randomized Controlled Trial of Paracervical Block
Intravenous Ketorolac Administration to Attenuate Post-procedural Pain Associated With Intrauterine Device Placement: A Randomized, Double-Blind, Placebo-Controlled Trial
Expanding the Use of Paracervical Block for IUD Placements and Adding a Compassionate Care Assessment
Empathy Through Pain Control: Buffered Compared to Unbuffered 1% Lidocaine During IUD Placement
Expanding the Use of Paracervical Block for IUD Placements and Adding a Compassionate Care Assessment- Aim 3
Pain Related to Local Anesthetic Administration for Nexplanon Placement: A Randomized Control Trial of Buffered Lidocaine
Transcutaneous Electrical Nerve Stimulation (TENS) for Intrauterine Device (IUD) Pain
Paracervical Block for Saline Infusion Sonogram in Fertility Evaluation: A Randomized Controlled Trial
The PLAN IUD Trial: The Effectiveness of Topical Prilocaine-Lidocaine Cream Plus Acetaminophen and Naproxen Compared to Lidocaine Injection Plus Acetaminophen and Naproxen to Manage Pain During IntraUterine Device Insertion: A Randomized Controlled Trial
Who cites it
23 citing papers in PubMed, 72 citations in OpenAlex.
- Analgesic effects of LI4 acupuncture during intrauterine device insertion: a randomized controlled clinical trial.Archives of gynecology and obstetrics · 2023Trial
- Use of naproxen versus intracervical block for pain control during the 52-mg levonorgestrel-releasing intrauterine system insertion in young women: a multivariate analysis of a randomized controlled trial.BMC women's health · 2021Trial
- Anticipated Pain During Intrauterine Device Insertion.Journal of pediatric and adolescent gynecology · 2020Trial
- Optimal Timing for Intrauterine Device Insertion During the Menstrual Cycle: A Comparative Study of Pain, Bleeding, and Postprocedural Outcomes.Clinics and practice · 2026Article
- Viral but Not Verified: Analyzing Accuracy and Engagement in TikTok Discussions of IUDs.Healthcare (Basel, Switzerland) · 2026Article
- Use of Paracervical Blocks for Patients Who Undergo Intrauterine Device Insertion.JAMA network open · 2026Article
- Optimization of injections with speculum-compatible devices to deliver ethyl cellulose-ethanol into the cervix to treat cervical dysplasia.Scientific reports · 2025Article
- Optimization of injections with speculum-compatible devices to deliver ethyl cellulose-ethanol into the cervix to treat cervical dysplasia.Research square · 2025Article
- Usability of Speculum-Compatible Injection Devices for Administering Ethyl Cellulose-Ethanol Ablation to Treat Cervical Neoplasia in Low- and Middle-Income Countries.Annals of biomedical engineering · 2025Article
- Differences in pain regimens among nulliparous patients undergoing intrauterine device placement within a single health system.American journal of obstetrics and gynecology · 2025Article
- Pain With Early Postpartum Intrauterine Device Placement.O&G open · 2025Article
- Article
- Effect of intracervical block on self-reported intrauterine device insertion pain: a single-center prospective survey study.Proceedings (Baylor University. Medical Center) · 2025Article
- Network Meta-Analysis of Randomized Controlled Trials Comparing Safety and Efficacy of Pharmacological Treatments in Reducing Pain During Intrauterine Device Insertion.Sultan Qaboos University medical journal · 2025Review
- Evaluation of Pain During Hysteroscopy Under Local Anesthesia, Including the Stages of the Procedure.Journal of clinical medicine · 2024Article
- Pain Management During Intrauterine Device Insertion in Nulliparous Women: A Scoping Review.Cureus · 2024Article
- Provider Perspectives on Analgesic Use in Intrauterine Device Insertion Procedures: A Mixed Methods Analysis.Cureus · 2024Article
- Differing Approaches to Pain Management for Intrauterine Device Insertion and Maintenance: A Scoping Review.Cureus · 2024Article
- Effective analgesic options for intrauterine device placement pain.Canadian family physician Medecin de famille canadien · 2020Article
- Interventions for the prevention of pain associated with the placement of intrauterine contraceptives: An updated review.Acta obstetricia et gynecologica Scandinavica · 2019Review
Corrections and comments
- Commented on by
- Commented on byIn Reply.2019
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo investigate whether a 20-mL buffered 1% lidocaine paracervical block decreases pain during intrauterine device (IUD) placement.
methodsIn a randomized, single-blind, placebo-controlled trial, women were assigned to receive either a 20-mL buffered 1% lidocaine paracervical block or no block before IUD placement. The primary outcome was pain with IUD placement measured on a 100-mm visual analog scale. Our sample size had 80% power (α=0.05) to detect a 20-mm difference in visual analog scale scores with a SD of 28 mm. Secondary outcomes included pain with speculum placement, paracervical block administration, tenaculum placement, 5 minutes postprocedure, and overall pain perception.
resultsFrom October 7, 2014, through October 26, 2017, 64 women were enrolled and analyzed (33 in the paracervical block arm, 31 in the no-block arm). There were no differences in baseline demographics between the groups. Women who received the paracervical block reported less pain with IUD placement compared with women who received no block (median visual analog scale score of 33 mm vs 54 mm, P=.002). Pain was significantly less in the intervention group for uterine sounding (30 mm vs 47 mm, P=.005), 5 minutes after placement (12 mm vs 27 mm, P=.005), and overall pain perception (30 mm vs 51 mm, P=.015). Participants who received the paracervical block experienced more pain with block administration compared with placebo (30 mm vs 8 mm, P=.003). There was no perceived pain difference for speculum insertion (10 mm vs 6 mm, P=.447) or tenaculum placement (15 mm vs 10 mm, P=.268).
conclusionA 20-mL buffered 1% lidocaine paracervical block decreases pain with IUD placement (primary outcome), uterine sounding (secondary outcome), and 5 minutes after placement (secondary outcome). Although paracervical block administration can be painful, perception of pain for overall IUD placement procedure is lower compared with no block. CLINICAL
trial registrationClinicalTrials.gov, NCT02219308.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.