Evidence map›Paper›PMID 30095564›Full record

ArticleJournal of addiction medicine

Commentary on "The More Things Change: Buprenorphine/Naloxone Diversion Continues While Treatment is Inaccessible".

Shannon Gwin Mitchell, Jan Gryczynski, Robert P Schwartz

Abstract readComment
In one paragraph

Article in Journal of addiction medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Observational
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Shannon Gwin MitchellFriends Research Institute, Baltimore, MD.
Jan Gryczynski
Robert P Schwartz
National Institute on Drug Abuse · US

Funding

Health Services Research: Extended Release Naltrexone for Opioid-Dependent YouthR01DA033391 · NIDA · FRIENDS RESEARCH INSTITUTE, INC. · PI MITCHELL, SHANNON GWIN · 2013 to 2018
$3.3M
NIDA NIH HHS R01 DA033391
6 · The paper itself

Abstract

: This commentary puts the recent findings by Carroll et al into historical perspective, noting both the long-held problem of medication diversion when pharmacotherapy access is limited, and the ways in which medication diversion concerns and regulations help create those treatment access barriers. Recent efforts to bridge the treatment gap, including increases in Federal funding through the 21st Century Cures Act and expanding the buprenorphine patient cap and scope of eligible providers under the Comprehensive Addiction Recovery Act (CARA) will likely help; however, important structural barriers remain. Health insurance barriers, including limited Medicaid coverage, combined with stigma against pharmacotherapy persist, which likely means that people in need of treatment will continue to self-treat their symptoms with diverted medications, such as the buprenorphine/naloxone use noted by Carroll and colleagues.

Indexed as

BuprenorphineOpioid-Related DisordersBuprenorphine, Naloxone Drug CombinationHumansMedicaidOpiate Substitution TreatmentBuprenorphineBuprenorphine, Naloxone Drug Combination

Identifiers

PMID30095564
PMCPMC6214742
OpenAlexW2887155213

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.