ArticleAllergy and asthma proceedings2018
Allergic sensitization and clinical outcomes in urban children with asthma, 2013-2016.
Article in Allergy and asthma proceedings, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Atopic dermatitis phenotype affects expression of atopic diseases despite similar mononuclear cell cytokine response.The Journal of allergy and clinical immunology · 2024Article
- Prevalence of Sensitization to Aeroallergens in Greater Beijing Region Children With Respiratory Allergy.Frontiers in pediatrics · 2022Article
- A novel computed tomography radiomic nomogram for early evaluation of small airway dysfunction development.Frontiers in medicine · 2022Article
- The efficacy of Tuina for asthma: A protocol for a systematic review and meta-analysis.Medicine · 2020Article
- Remission of persistent childhood asthma: Early predictors of adult outcomes.The Journal of allergy and clinical immunology · 2019Article
- Children are not small adults.Allergy and asthma proceedings · 2018Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to examine if food and/or aeroallergen sensitization was associated with worse asthma, pulmonary function tests (PFT), and laboratory markers.
methodsAt our institution, 386 children with asthma were divided into allergic and nonallergic groups based on allergen-specific immunoglobulin E (IgE) testing classes 1-6 versus 0. Asthma severity and/or control, IgE level, eosinophil counts and/or percentages, forced vital capacity (FVC), forced expiratory volume in the first second of expiration (FEV1), and FEV1/FVC, were compared by using bivariate, regression, and subgroup analyses for children who were highly allergic (≥4 allergens).
resultsA total of 291 subjects with asthma were allergic, significantly older, and had higher mean IgE levels and eosinophil counts and percentages (all p < 0.001). A total of 203 subjects who were highly allergic had worse obstruction on PFTs. Increasing age predicted allergen sensitization after confounder adjustment, odds ratio (OR) 1.54 (95% confidence interval [CI], 1.18-2.02). Similarly, PFT obstruction was associated with multiple allergen sensitization (OR 0.97 [95% CI, 0.93-1.02]).
conclusionIncreasing age predicted allergic sensitization and multiple allergen sensitization. Worse obstruction on PFT also predicted multiple allergen sensitization. Continued surveillance of aeroallergen sensitization and PFT results may be beneficial in asthma management, particularly in older urban children.
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