Evidence map›Paper›PMID 30095186›Full record

ArticleEnvironmental and molecular mutagenesis2018

Global metabolomic responses in urine from atm deficient mice in response to LD

Evagelia C Laiakis, Tytus D Mak, Steven J Strawn, Yi-Wen Wang, Bo-Hyun Moon, Pelagie Ake, Albert J Fornace

Abstract read
In one paragraph

Article in Environmental and molecular mutagenesis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Evagelia C LaiakisDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia.
Tytus D MakMass Spectrometry Data Center, National Institute of Standards and Technology (NIST), Gaithersburg, Maryland.
Steven J StrawnDepartment of Biochemistry and Molecular & Cellular Biology, Georgetown University, Washington, District of Columbia.
Yi-Wen WangDepartment of Biochemistry and Molecular & Cellular Biology, Georgetown University, Washington, District of Columbia.
Bo-Hyun MoonDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia.
Pelagie AkeDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia.
Albert J FornaceDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia.
Georgetown University · USGeorgetown University Medical Center · USNational Institute of Standards and Technology · US

Funding

Sample Engineering CoreU19AI067773 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FORNACE, ALBERT J · 2005 to 2024
$105.4M
Tissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI Louis M Weiner · 1990 to 2026
$71.5M
NCI NIH HHS P30 CA051008NIAID NIH HHS U19 AI067773
6 · The paper itself

Abstract

Exposures to ionizing radiation (IR) may either be accidental or intentional, for medical purposes or even through terrorist actions. As certain populations emerge to be more radiosensitive than others, it is imperative to assess those individuals and treat them accordingly. To demonstrate the feasibility of rapid identification of such cases, we utilized the highly radiosensitive mouse model Atm

Indexed as

Gene DeletionAnimalsAtaxia Telangiectasia Mutated ProteinsDose-Response Relationship, RadiationGamma RaysGenotypeLethal Dose 50MaleMetabolic Networks and PathwaysMetabolomeMetabolomicsMice, Inbred C57BLUrinalysisUrineAtaxia Telangiectasia Mutated ProteinsAtm protein, mouseataxia telangiectasia mutatedbiodosimetryionizing radiationmetabolomicsurine

Identifiers

PMID30095186
PMCPMC6113093
OpenAlexW2885642818

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.