Evidence map›Paper›PMID 30095157›Full record

ReviewBritish journal of pharmacology2019

Inflammatory mediators: a causal link to hypertension during preeclampsia.

Denise C Cornelius, Jesse Cottrell, Lorena M Amaral, Babbette LaMarca

Open access · bronzeAbstract readReview
In one paragraph

Review in British journal of pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 4 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 4 syntheses or guidelines pooled it, 85 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Review
  7. Article
  8. Article
  9. Article
  10. Extracellular vesicles in preeclampsia: drivers of vascular dysfunction and inflammation.American journal of physiology. Heart and circulatory physiology · 2025
    Review
  11. Review
  12. Revealing the Complexity of Immunobiological Shifts From Non-Pregnant to Pregnant State.American journal of reproductive immunology (New York, N.Y. : 1989) · 2025
    Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. IL-33 Signaling Inhibition Leads to a Preeclampsia-Like Phenotype in Pregnant Rats.American journal of reproductive immunology (New York, N.Y. : 1989) · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Denise C CorneliusDepartment of Pharmacology, University of Mississippi Medical Center, Jackson, MS, USA.
Jesse CottrellDepartment of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson, MS, USA.
Lorena M AmaralDepartment of Emergency Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
Babbette LaMarcaDepartment of Pharmacology, University of Mississippi Medical Center, Jackson, MS, USA.ORCID 0000-0002-3340-6088
Jackson Memorial Hospital · USUniversity of Mississippi Medical Center · US

Funding

Role of obesity in preeclamptic pregnancy.P20GM121334 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI Noha Shawky Elsayed · 2017 to 2026
$26.4M
The Kidney, Hypertension, Pregnancy and InflammationR01HD067541 · NICHD · UNIVERSITY OF MISSISSIPPI MED CTR · PI LAMARCA, BABBETTE · 2011 to 2020
$3.1M
Hypertension and InflammationR00HL130456 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI CORNELIUS, DENISE CRESHUN · 2017 to 2019
$747k
Hypertension and InflammationK99HL130456 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI CORNELIUS, DENISE CRESHUN · 2016 to 2016
$136k
NHLBI NIH HHS K99 HL130456NHLBI NIH HHS R00 HL130456NICHD NIH HHS R01 HD067541NIGMS NIH HHS P20 GM121334
6 · The paper itself

Abstract

Preeclampsia (PE) is a hypertensive disorder that occurs after 20 weeks of gestation, implicating the placenta as a key offender. PE is associated with an imbalance among B lymphocytes, CD4

Indexed as

AnimalsCytokinesFemaleHumansHypertensionInflammation MediatorsPre-EclampsiaPregnancyT-Lymphocytes, RegulatoryCytokinesInflammation Mediators

Identifiers

PMID30095157
PMCPMC6534812
OpenAlexW2885969410

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.